List of side effects of buspirone explained

Side effects of buspirone by incidence include:^{[1] [2] [3] [4]}

Very common (>10% incidence)

• Dizziness/lightheadedness
• Headache
• Somnolence (sleepiness)

Common (1–10% incidence)

• Nervousness
• Insomnia
• Sleep disorder
• Disturbance in attention
• Depression
• Confusional state
• Anger
• Tachycardia (fast heart rate)
• Chest pain
• Sinusitis (nasal congestion)
• Pharyngolaryngeal pain
• Paraesthesia (tingling skin)
• Blurred vision
• Abnormal coordination
• Tremor
• Cold sweat
• Rash
• Nausea
• Abdominal pain
• Dry mouth
• Diarrhea
• Constipation
• Vomiting
• Fatigue
• Musculoskeletal pain

Uncommon (0.1–1%)

• Syncope
• Hypotension
• Hypertension
• Redness and itching of the eyes
• Altered taste
• Conjunctivitis
• Flatulence
• Anorexia
• Increased appetite
• Salivation
• Rectal bleeding
• Urinary frequency
• Urinary hesitancy
• Menstrual irregularity or spotting
• Dysuria
• Muscle cramps
• Muscle spasms
• Muscle rigidity/stiffness
• Involuntary movements
• Shortness of breath
• Chest congestion
• Changes in libido
• Oedema
• Pruritus
• Flushing
• Easy bruising
• Dry skin
• Facial oedema
• Mild increases in hepatic aminotransferases (AST, ALT)
• Weight gain
• Fever
• Roaring sensation in the head
• Weight loss
• Malaise
• Depersonalisation
• Noise intolerance
• Euphoria
• Akathisia
• Fearfulness
• Loss of interest
• Dissociative reaction

Rare (<0.1% incidence)

• Cerebrovascular accident (stroke)
• Myocardial infarction (heart attack)
• Cardiomyopathy
• Congestive heart failure
• Bradycardia
• Dysphoria
• Hallucinations
• Feelings of claustrophobia
• Cold intolerance
• Stupor
• Seizures
• Slurred speech
• Extrapyramidal symptoms including dyskinesias (acute & delayed)
• Dystonic reactions
• Cogwheel rigidity
• Emotional lability
• Psychosis
• Suicidal ideation
• Ataxias
• Transient difficulty with recall
• Serotonin syndrome
• Parkinsonism
• Restless leg syndrome
• Restlessness
• Eye pain
• Altered sense of smell
• Photophobia
• Pressure on eyes
• Inner ear abnormality
• Tunnel vision
• Galactorrhoea
• Irritable bowel syndrome
• Burning of the tongue
• Arthralgias
• Amenorrhoea (cessation of menstrual cycles)
• Enuresis
• Nocturia
• Pelvic inflammatory disease
• Urinary retention
• Hyperventilation
• Epistaxis
• Delayed ejaculation
• Impotence
• Acne
• Hair loss
• Blisters
• Thinning of nails
• Allergic reactions including urticaria, ecchymosis, angioedema
• Eosinophilia
• Leucopenia
• Thrombocytopaenia
• Excessive use of alcohol
• Bleeding disturbance
• Loss of voice
• Hiccups
• Thyroid abnormality

Notes and References

1. Web site: buspirone (Rx) - BuSpar, Buspirex, more... Medscape Reference. WebMD. 14 November 2013.
2. Web site: BUSPIRONE HCL (buspirone hydrochloride) tablet [Watson Laboratories, Inc.]]. DailyMed. Watson Laboratories, Inc.. July 2013. 14 November 2013.
3. Web site: BUSPAR® (buspirone hydrochloride) Tablets 5 mg & 10 mg PRODUCT INFORMATION. TGA eBusiness Services. Aspen Pharma Pty Ltd. January 2010. 14 November 2013. PDF.
4. Web site: Buspirone 10mg Tablets. electronic Medicines Compendium. Actavis UK Ltd. 10 September 2012. 14 November 2013.