This is a list of pizza chains of the United States. This list is limited to pizza chain restaurants that are based, headquartered or originated in the United States.
The distinction between national chains and primarily regional chains is only indicative of geographic footprint and not necessarily of the overall size of the chain. For example, Grimaldi's Pizzeria is a national chain with 47 locations,[1] while Casey's is a Fortune 500 company with 2,500 locations despite almost exclusively serving the Midwestern United States.[2]