The Portuguese Singles Chart ranks the best-performing singles in Portugal, as compiled by the Associação Fonográfica Portuguesa.
| Week | Song | Artist | Reference |
|---|---|---|---|
| 1/2016 | "Sorry" | Justin Bieber | [1] |
| 2/2016 | [2] | ||
| 3/2016 | [3] | ||
| 4/2016 | [4] | ||
| 5/2016 | "Pillowtalk" | Zayn | [5] |
| 6/2016 | "Love Yourself" | Justin Bieber | [6] |
| 7/2016 | [7] | ||
| 8/2016 | "Work" | Rihanna featuring Drake | [8] |
| 9/2016 | [9] | ||
| 10/2016 | [10] | ||
| 11/2016 | [11] | ||
| 12/2016 | [12] | ||
| 13/2016 | [13] | ||
| 14/2016 | "Cheap Thrills" | Sia | [14] |
| 15/2016 | [15] | ||
| 16/2016 | [16] | ||
| 17/2016 | [17] | ||
| 18/2016 | "One Dance" | Drake featuring Wizkid and Kyla | [18] |
| 19/2016 | [19] | ||
| 20/2016 | [20] | ||
| 21/2016 | [21] | ||
| 22/2016 | [22] | ||
| 23/2016 | [23] | ||
| 24/2016 | [24] | ||
| 25/2016 | [25] | ||
| 26/2016 | [26] | ||
| 27/2016 | [27] | ||
| 28/2016 | "This One's for You" | David Guetta featuring Zara Larsson | [28] |
| 29/2016 | [29] | ||
| 30/2016 | "One Dance" | Drake featuring Wizkid and Kyla | [30] |
| 31/2016 | "Cold Water" | Major Lazer featuring Justin Bieber and MØ | [31] |
| 32/2016 | [32] | ||
| 33/2016 | [33] | ||
| 34/2016 | [34] | ||
| 35/2016 | "Closer" | The Chainsmokers featuring Halsey | [35] |
| 36/2016 | [36] | ||
| 37/2016 | [37] | ||
| 38/2016 | [38] | ||
| 39/2016 | [39] | ||
| 40/2016 | [40] | ||
| 41/2016 | [41] | ||
| 42/2016 | [42] | ||
| 43/2016 | [43] | ||
| 44/2016 | [44] | ||
| 45/2016 | "Starboy" | The Weeknd featuring Daft Punk | [45] |
| 46/2016 | [46] | ||
| 47/2016 | [47] | ||
| 48/2016 | [48] | ||
| 49/2016 | [49] | ||
| 50/2016 | [50] | ||
| 51/2016 | [51] | ||
| 52/2016 | [52] |