This is a list of the weekly Canadian RPM magazine number one Top Singles chart of 1966.
| Volume:Issue | Issue Date(s) | Song | Artist | |
| 4:19 | 3 January | "Flowers on the Wall" | Statler Brothers | |
| 4:20 | 10 January | "Five O'Clock World" | The Vogues | |
| 4:21 | 17 January | "No Matter What Shape (Your Stomach's In)" | The T-Bones | |
| 4:22 | 24 January | "We Can Work It Out" | The Beatles | |
| 4:23 | 31 January | "Yesterday Man" | Chris Andrews | |
| 4:24 | 7 February | "As Tears Go By" | The Rolling Stones | |
| 4:25 | 14 February | "My Love" | Petula Clark | |
| 4:26 | 21 February | "Lightnin' Strikes" | Lou Christie | |
| 5:1 | 28 February | "Michelle" | David and Jonathan | |
| 5:2 | 7 March | "These Boots Are Made for Walking" | Nancy Sinatra | |
| 5:3 | 14 March | "At the Scene" | Dave Clark 5 | |
| 5:4 | 21 March | "Listen People" | Herman's Hermits | |
| 5:5 | 28 March | "Nowhere Man" | The Beatles | |
| 5:6 | 4 April | "Woman" | Peter & Gordon | |
| 5:7 | 11 April | "Magic Town" | The Vogues | |
| 5:8 | 18 April | "Daydream" | The Lovin' Spoonful | |
| 5:9 | 25 April | "Good Lovin'" | The Young Rascals | |
| 5:10 | 2 May | "Kicks" | Paul Revere & the Raiders | |
| 5:11 | 9 May | "Good Lovin'" | The Young Rascals | |
| 5:12 | 16 May | "Monday, Monday" | The Mamas & the Papas | |
| 5:13 | 23 May | |||
| 5:14 | 30 May | |||
| 5:15 | 6 June | "When a Man Loves a Woman" | Percy Sledge | |
| 5:16 | 13 June | "Paint It, Black" | The Rolling Stones | |
| 5:17 | 20 June | "Green Grass" | Gary Lewis | |
| 5:18 | 27 June | "Sweet Talkin' Guy" | The Chiffons | |
| 5:19 | 4 July | "Paperback Writer" | The Beatles | |
| 5:20 | 11 July | "Red Rubber Ball" | The Cyrkle | |
| 5:21 | 18 July | "The Pied Piper" | Crispian St. Peters | |
| 5:22 | 25 July | "Hanky Panky" | Tommy James and the Shondells | |
| 5:23 | 1 August | "Sweet Pea" | Tommy Roe | |
| 5:24 | 8 August | "I Saw Her Again" | The Mamas & the Papas | |
| 5:25 | 15 August | "Summer in the City" | The Lovin' Spoonful | |
| 5:26 | 22 August | |||
| 6:1 | 29 August | "See You in September" | The Happenings | |
| 6:2 | 5 September | "Bus Stop" | The Hollies | |
| 6:3 | 12 September | "Get Away" | Georgie Fame | |
| 6:4 | 19 September | "Yellow Submarine"/"Eleanor Rigby" | The Beatles | |
| 6:5 | 26 September | "Sunny Afternoon" | The Kinks | |
| 6:6 | 3 October | "Cherish" | The Association | |
| 6:7 | 10 October | "Black Is Black" | Los Bravos | |
| 6:8 | 17 October | "See See Rider" | Eric Burdon and The Animals | |
| 6:9 | 24 October | |||
| 6:10 | 31 October | "96 Tears" | Question Mark & the Mysterians | |
| 6:11 | 7 November | "Last Train to Clarksville" | The Monkees | |
| 6:12 | 14 November | "Dandy" | Herman's Hermits | |
| 6:13 | 21 November | "Poor Side of Town" | Johnny Rivers | |
| 6:14 | 28 November | "Winchester Cathedral" | New Vaudeville Band | |
| 6:15 | 5 December | |||
| 6:16 | 12 December | "Lady Godiva" | Peter & Gordon | |
| 6:17 | 19 December | "Stop! Stop! Stop!" | The Hollies | |
| 6:18 | 26 December | "I'm a Believer" | The Monkees |