These are the Billboard Hot Dance/Disco Club Play and Maxi-Singles Sales number-one hits of 2003.
| Issue date | Club Play | Artist | Maxi-Singles Sales | Artist | Reference(s) |
|---|---|---|---|---|---|
| January 4 | "Dark Beat (Addicted 2 Drums)" | Oscar G and Ralph Falcón | "Die Another Day" (Remixes) | Madonna | [1] [2] |
| January 11 | [3] | ||||
| January 18 | "Like I Love You" | Justin Timberlake | [4] | ||
| January 25 | "Some Lovin'" | Murk featuring Kristine W | [5] | ||
| February 1 | "Surrender" | Laura Pausini | [6] | ||
| February 8 | "Through the Rain" | Mariah Carey | [7] | ||
| February 15 | "Head" | Thunderpuss and Barnes | [8] | ||
| February 22 | "Emotional Rollercoaster" | Vivian Green | [9] | ||
| March 1 | "The Wreckoning" | Boomkat | "Through the Rain" (Hex Hector/Mac Quayle Remix) | Mariah Carey | [10] |
| March 8 | "Rise Up" | Funky Green Dogs | "Cry Me A River" (Dirty Vegas, J. Fiasco, & B. Hamel Mixes) | Justin Timberlake | [11] |
| March 15 | "The Hum Melody" | Robbie Rivera | [12] | ||
| March 22 | "Dance to the Rhythm" | Friburn & Urik | [13] | ||
| March 29 | "I Believe" | Chris Cox vs. Happy Clappers | [14] | ||
| April 5 | "When the Money's Gone" | Cher | [15] | ||
| April 12 | "Try It on My Own" | Whitney Houston | "If You're Not The One" (Remixes) | Daniel Bedingfield | [16] |
| April 19 | "Beautiful" | Christina Aguilera | [17] | ||
| April 26 | "On a High" | Duncan Sheik | [18] | ||
| May 3 | "Gossip Folks" | Missy "Misdemeanor" Elliott featuring Ludacris | [19] | ||
| May 10 | "Walking on Thin Ice" | Ono | [20] | ||
| May 17 | "I'll Be There" | Weekend Players | "American Life" | Madonna | [21] |
| May 24 | "Love Is a Crime" | Anastacia | "If You're Not The One" (Remixes) | Daniel Bedingfield | [22] |
| May 31 | "American Life" | Madonna | [23] | ||
| June 7 | "Rock Your Body" | Justin Timberlake | [24] | ||
| June 14 | "If That's Love" | Laura Pausini | [25] | ||
| June 21 | "Love That Man" | Whitney Houston | [26] | ||
| June 28 | "Getaway" | Becky Baeling | "Getaway" | Becky Baeling | [27] |
| July 5 | "Not Gonna Get Us" | t.A.T.u. | "Stuck" (Thunderpuss Remix) | Stacie Orrico | [28] |
| July 12 | "Play Your Part" | Deborah Cox | [29] | ||
| July 19 | "So Gone" | Monica | [30] | ||
| July 26 | "Intuition" | Jewel | "Hollywood" (Remixes) | Madonna | [31] |
| August 2 | "Alright" | Murk | [32] | ||
| August 9 | "Pavement Cracks" | Annie Lennox | [33] | ||
| August 16 | [34] | ||||
| August 23 | "Hollywood" | Madonna | [35] [36] | ||
| August 30 | "Sunrise" | Simply Red | "Stuck" (Thunderpuss Remix) | Stacie Orrico | [37] |
| September 6 | "Harem" | Sarah Brightman | "Officially Missing You" (Remixes) | Tamia | [38] |
| September 13 | "Crazy in Love" | Beyoncé featuring Jay-Z | "Hollywood" (Remixes) | Madonna | [39] |
| September 20 | "My Time" | Dutch featuring Crystal Waters | [40] | ||
| September 27 | "Get It Together" | Seal | "Rubberneckin'" (Paul Oakenfold Remix) | Elvis Presley | [41] |
| October 4 | "Sympathy For The Devil" (Remixes) | The Rolling Stones | [42] | ||
| October 11 | "Into the Sun" | Weekend Players | "Rubberneckin'" (Paul Oakenfold Remix) | Elvis Presley | [43] |
| October 18 | "Send Your Love" | Sting | [44] | ||
| October 25 | "I Love I Love" | Georgie Porgie | [45] | ||
| November 1 | "Lei Lo Lai" | The Latin Project | [46] | ||
| November 8 | "What U Do 2 Me" | Boomkat | [47] | ||
| November 15 | "This Beat Is" | Superchumbo | [48] | ||
| November 22 | "Stand" | Jewel | [49] | ||
| November 29 | "Fly Again" | Kristine W | [50] | ||
| December 6 | "Milkshake" | Kelis | [51] | ||
| December 13 | "Waiting for You" | Seal | [52] | ||
| December 20 | "Believe" | Murk | [53] | ||
| December 27 | "Me Against the Music" | Britney Spears featuring Madonna | "Nothing Fails" / "Nobody Knows Me" | Madonna | [54] |