| Train Name | Railroad | Train Endpoints | Operated |
|---|
| Aare Linth | SOB | Chur - Zurich (Hauptbahnhof) - Bern | 2021–present |
| AB-Klassiker | AB | Appenzell - Wasserauen | present |
| Aqualino[1] | RhB | Scuol-Tarasp - Chur - Disentis/Muster | present |
| Bernina Express | RhB | Chur - St. Moritz - Tirano | present |
| CNL Apus | CNL | Amsterdam (Centraal) - Bellinzona - Milan (Central) | present |
| CNL Aurora | CNL | Zurich (Hauptbahnhof) - Copenhagen (Central) | present |
| CNL Berliner | CNL | Zurich (Hauptbahnhof) - Berlin (Hauptbahnhof) | present |
| CNL Canopus | CNL | Zurich (Hauptbahnhof) - Prague (Central) | present |
| CNL Komet | CNL | Zurich (Hauptbahnhof) - Hamburg (Hauptbahnhof) | present |
| CNL Orion | CNL | Basel - Dresden (Hauptbahnhof) - Prague (Main) | present |
| CNL Pegasus | CNL | Amsterdam (Centraal) - Zurich (Hauptbahnhof) - Brig | present |
| CNL Semper | CNL | Zurich (Hauptbahnhof) - Dresden (Hauptbahnhof) | present |
| EC Borromeo | Cisalpino | Basel - Bern (Main) - Milan (Central) | present |
| EC Canaletto | Cisalpino | Zurich (Hauptbahnhof) - Venice (Santa Lucia) | present |
| EC Cinque Terre | Cisalpino | Zurich (Hauptbahnhof) - La Spezia | present |
| EC Iris | SNCB, CFL, SNCF, SBB CFF FFS | Brussels (Midi/Zuid) - Strasbourg - Chur | present |
| EC Jean Monet | SNCB, CFL, SNCF | Brussels (Midi/Zuid) - Strasbourg - Basel | present |
| EC Kaiserin Elisabeth | SBB CFF FFS, ÖBB | Zurich (Hauptbahnhof) - Salzburg | present |
| EC Lemano | Cisalpino | Geneva - Milan (Central) | present |
| EC Maria Theresia | SBB CFF FFS, ÖBB | Zurich (Hauptbahnhof) - Vienna (Westbahnhof) | present |
| EC Monte Rosa | Cisalpino | Geneva - Milan (Central) | present |
| EC Ticino | SBB CFF FFS, FS/Trenitalia, Cisalpino | Basel - Lucerne - Milan (Central) | 1993–2008 |
| EC Transalpin | SBB CFF FFS, ÖBB | Basel - Vienna (Westbahnhof) | 1958–2010 |
| EC Vall D’Ossola | Cisalpino | Basel - Bern (Main) - Milan (Central) | present |
| EC Vallese | Cisalpino | Geneva - Milan (Central) | present |
| EC Vauban | SNCB, CFL, SNCF, SBB CFF FFS | Brussels (Midi/Zuid) - Strasbourg - Brig | present |
| EC Verbano | Cisalpino | Basel - Bern (Main) - Milan (Central) | present |
| EN Roma | SBB CFF FFS, Trenitalia | Zurich (Hauptbahnhof) - Venice (Santa Lucia)
Zurich (Hauptbahnhof) - Rome (Termini) | present |
| EN Wiener Walzer | SBB CFF FFS, ÖBB, MÁV | Zurich (Hauptbahnhof) - Prague (Main)
Zurich (Hauptbahnhof) - Vienna (Westbahnhof) - Budapest (Keleti) | present |
| EN Zürichsee | SBB CFF FFS, ÖBB, SŽ, HŽ, ŽS | Zurich (Hauptbahnhof) - Ljubljana (Main) - Zagreb - Beograd | present |
| Engadin Star[2] | RhB | Landquart - St. Moritz | present |
| Glacier Express | MGB, RhB | Zermatt - St. Moritz | present |
| Glarner Sprinter | SBB CFF FFS | Zurich (Hauptbahnhof) - Linthal | 2004–2014 |
| GoldenPass Line | Zentralbahn, BLS, Montreux–Lenk im Simmental line | Lucerne - Interlaken - Zweisimmen - Montreux | present |
| Gotthard Panorama Express | SBB CFF FFS, SGV | (Lucerne by boat to) Flüelen - Bellinzona - Lugano | present |
| Heidi Express (currently the Bernina Express) | RhB | Chur - St. Moritz - Tirano | present |
| IC Brianza | Cisalpino | Bellinzona - Milan (Central) | present |
| IC Insubria | SBB CFF FFS, Trenitalia | Stuttgart (Hauptbahnhof) - Zurich (Hauptbahnhof) - Milan (Central) | present |
| IC Mediolanum | SBB CFF FFS, Trenitalia | Basel - Lucerne - Milan (Central) | present |
| IC Monte Ceneri | Cisalpino | Zurich (Hauptbahnhof) - Milan (Central) | present |
| IC Riviera dei Fiori | Cisalpino | Basel - Lucerne - Genova - Nice | present |
| IC Teodolina | Cisalpino | Zurich (Hauptbahnhof) - Milan (Central) | present |
| IC Tiziano | SBB CFF FFS, Trenitalia | Basel - Lucerne - Milan (Central) | present |
| IC Verdi | SBB CFF FFS, Trenitalia | Basel - Lucerne - Milan (Central) | present |
| RE Lötschberg[3] | BLS | Spiez - Kandersteg - Goppenstein (Lötschental) - Brig | present |
| Rheingold | | Basel - Hook of Holland | 1934–1987 |
| Rheintal Express | SBB CFF FFS | St. Gallen - Chur | present |
| TEE Gottardo | SBB CFF FFS, FS | Zurich - Milan (Central) | 1961–1988 |
| TEE Ticino | SBB CFF FFS | Zurich - Milan (Central) | 1961–1974 |
| Train des Vignes | SBB CFF FFS | Vevey - Puidoux-Chexbres | present |
| Train du Chocolat[4] | TPF | Montreux - Gruyères - Broc | present |
| Train Fondue | TPF | (Montreux) - Montbovon - Bulle | present |
| Trenhotel Pau Casals | Elipsos | Zurich (Hauptbahnhof) - Barcelona (Estació de França) | present |
| Trenino della Neve | RhB | St. Moritz - Tirano | present |
| Treno Gottardo | SOB,SBB CFF FFS | Locarno - Airolo - Göschenen - Arth-Goldau - Zurich (Hauptbahnhof)Locarno - Airolo - Göschenen - Arth-Goldau - Basel (SBB) | 2020–present |
| Voralpen Express | SOB (until 2013 in collaboration with SBB CFF FFS) | Lucerne - Rapperswil - St. Gallen ( - Romanshorn, until 2013) | present | |
