| Post: | Mayor |
| Body: | Cheyenne, Wyoming |
| Insigniacaption: | Seal of Cheyenne |
| Incumbent: | Patrick Collins |
| Incumbentsince: | January 4, 2021 |
| Seat: | Cheyenne, Wyoming |
| Appointer: | Cheyenne City Council |
| Formation: | 1867 |
| First: | H. M. Hook |
The following is a list of mayors of Cheyenne, Wyoming. The current mayor is Patrick Collins.
| Party | Mayor[1] | Term start | Term end | |
|---|---|---|---|---|
| 1 | Nonpartisan | H. M. Hook | 1867 | 1868 |
| 2 | Democratic | Luke Murrin | 1868 | 1869 |
| 3 | Nonpartisan | W. W. Slaughter | 1869 | 1869 |
| 4 | Nonpartisan | J. H. Martin | 1870 | 1870 |
| 5 | Nonpartisan | Jervis Joslin | 1871 | 1872 |
| 6 | Nonpartisan | M. Sloan | 1872 | 1872 |
| 7 | Democratic | M. V. Boughton | 1873 | 1874 |
| 8 | Nonpartisan | George Cassels | 1874 | 1874 |
| 9 | Nonpartisan | I. C. Whipple | 1875 | 1875 |
| 10 | Nonpartisan | L. R. Bresnahan | 1876 | 1876 |
| 11 | Nonpartisan | D. Fisk | 1877 | 1877 |
| 12 | Nonpartisan | L. R. Bresnahan (2) | 1878 | 1879 |
| 13 | Nonpartisan | F. E. Addoms | 1880 | 1881 |
| 14 | Republican | Joseph M. Carey | 1881 | 1885 |
| 15 | Nonpartisan | Francis E. Warren | 1885 | 1885 |
| 16 | Nonpartisan | A. H. Reel | 1885 | 1886 |
| 17 | Nonpartisan | Charles W. Riner | 1887 | 1890 |
| 18 | Nonpartisan | L. R. Bresnahan (3) | 1891 | 1892 |
| 19 | Nonpartisan | Ed F. Stahle | 1893 | 1895 |
| 20 | Nonpartisan | Samuel Merrill | 1896 | 1897 |
| 21 | Nonpartisan | William R. Schnitger | 1897 | 1900 |
| 22 | Nonpartisan | J. L. Murray | 1901 | 1902 |
| 22 | Republican | Moses Patrick Keefe | 1903 | 1904 |
| 23 | Democratic | Daniel Webster Gill | 1905 | 1906 |
| 24 | Nonpartisan | P. S. Cook | 1907 | 1910 |
| 25 | Nonpartisan | L. R. Bresnahan (4) | 1911 | 1912 |
| 26 | Democratic | Daniel Webster Gill (2) | 1913 | 1914 |
| 27 | Nonpartisan | R. N. La Fontaine | 1914 | 1917 |
| 28 | Nonpartisan | Edward W. Stone | 1918 | 1919 |
| 29 | Nonpartisan | Ed P. Taylor | 1920 | 1923 |
| 30 | Nonpartisan | Archie Allison | 1924 | 1925 |
| 31 | Nonpartisan | Charles W. Riner (2) | 1926 | 1929 |
| 32 | Nonpartisan | Cal Holliday | 1930 | 1931 |
| 33 | Nonpartisan | J. F. Weyhrecht | 1932 | 1933 |
| 34 | Nonpartisan | Archie Allison (2) | 1934 | 1940 |
| 35 | Democratic | Ed Warren | 1940 | 1944 |
| 36 | Republican | Ira L. Hanna | 1944 | 1944 |
| 37 | Republican | Bruce S. Jones | 1944 | 1946 |
| 38 | Nonpartisan | John J. Mcinerney | 1946 | 1947 |
| 39 | Nonpartisan | Benjamin C. Nelson | 1949 | 1951 |
| 40 | Nonpartisan | Edward Gowdy | 1951 | 1951 |
| 41 | Democratic | Ed Warren (2) | 1951 | 1952 |
| 42 | Nonpartisan | R. E. Cheever | 1952 | 1954 |
| 43 | Nonpartisan | Val S. Christensen | 1954 | 1957 |
| 44 | Nonpartisan | Worth Story | 1958 | 1961 |
| 45 | Democratic | Bill Nation[2] | 1962 | 1965 |
| 46 | Nonpartisan | Bill Herbert Kingham | 1966 | 1967 |
| 47 | Nonpartisan | George R. Cox | 1968 | 1969 |
| 48 | Nonpartisan | Floyd Holland | 1970 | 1971 |
| 49 | Nonpartisan | James D. Van Velzor | 1972 | 1973 |
| 50 | Democratic | Bill Nation (2) | 1973 | 1976 |
| 51 | Nonpartisan | Donald Erickson | 1977 | 1988 |
| 52 | Nonpartisan | Gary Schaeffer | 1989 | 1992 |
| 53 | Nonpartisan | Leo Pando | 1993 | 2001 |
| 54 | Nonpartisan | Jack R. Spiker | 2001 | 2008 |
| 55 | Nonpartisan | Richard L. Kaysen | 2009 | 2016 |
| 56 | Republican | Marian Orr | 2017 | 2020 |
| 57 | Nonpartisan | Patrick Collins[3] | 2021 | present |