The following is a list of independent pharmaceutical, biotechnology and medical companies listed on a stock exchange (as indicated) with current market capitalization of at least US$10 billion, ranked by their market capitalization.
It does not include biotechnology companies that are currently owned by, or form a part of, larger pharmaceutical groups.
The following table lists the largest biotechnology and pharmaceutical companies ranked by market capitalization in billion US dollars. The change column indicates the company's relative position in this list compared to their relative position in the preceding year; i.e., an increase would be moving closer to rank 1 and vice versa.
| [1] | [2] [3] | [4] | [5] | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 399.9 (Dec 2020) | 399.99 | 385.0 | 346.1 | 375.4 | 314.1 | 284.2 | 277.8 | 258.3 | |||||
| 2 | 1 | 291.1 (Dec 2020) | 291.12 | 281.1 | 209.3 | 216.7 | 192.1 | 234.7 | 258.5 | 240.3 | ||||
| 3 | 2 | 310.5 (Jul 2000) | 208.11 | 216.7 | 259.7 | 215.9 | 196.3 | 199.3 | 205.4 | 196.0 | ||||
| 4 | 1 | 275.2 (Jul 2015) | 202.09 | 240.0 | 200.0 | 196.7 | 170.5 | 206.1 | 229.8 | 195.0 | ||||
| 5 | 1 | 232.9 (Dec 2019) | 201.80 | 232.9 | 205.8 | 153.3 | 164.3 | 147.6 | 166.9 | 146.5 | ||||
| 6 | https://www.equities.com/news/ultragenyx-pharmaceutical-inc-rare-breaks-into-new-52-week-high-on-december-14-session | 201 (Sep 2021) | 68.5 | 45.0 | - | |||||||||
| 7 | 190.4 (Dec 2020) | 190.44 | 153.5 | 126.8 | 99.3 | 56.4 | 67.0 | 67.9 | 59.3 | |||||
| 8 | 2 | 196.2 (Jan 2018) | 182.27 | 130.9 | 146.3 | 154.4 | 100.2 | 96.8 | 104.1 | 83.8 | ||||
| 9 | 161.9 (Dec 2020) | 161.99 | 137.1 | 111.9 | 131.2 | 92.6 | 153.9 | 125.4 | - | |||||
| 10 | 2 | 158.3 (Dec 2020) | 158.30 | 126.9 | 125.6 | 93.0 | 80.9 | 93.4 | 76.6 | 57.0 | ||||
| 11 | 3 | NASDAQ: | 137.8 (Dec 2020) | 137.85 | 105.0 | 85.0 | 100.3 | 98.2 | 114.8 | 97.6 | 87.2 | |||
| 12 | 4 | NASDAQ: | 145.8 (Dec 2019) | 129.79 | 144.6 | 128.8 | 126.2 | 108.9 | 122.5 | 93.1 | 78.7 | |||
| 13 | 2 | 130.8 (Dec 2019) | 129.44 | 130.8 | 96.2 | 87.9 | 68.8 | 85.8 | 88.9 | 74.6 | ||||
| 14 | 4 | 151.3 (Sep 2014) | 120.66 | 63.5 | 108.4 | 108.2 | 101.8 | 111.8 | 138.1 | 142.0 | ||||
| 15 | 2 | 174.9 (May 2006) | 90.15 | 117.2 | 94.8 | 87.9 | 93.3 | 97.6 | 128.9 | 129.6 | ||||
| 16 | 1 | 88.8 (Dec 2020) | 88.81 | 78.5 | 58.6 | 58.0 | 45.1 | 34.7 | 35.7 | 28.4 | ||||
| 17 | 2 | NASDAQ: | 76.6 (Aug 2020) | 75.97 | 63.2 | 41.4 | 35.1 | 26.4 | 23.8 | 21.6 | 16.3 | |||
| 18 | 3 | NASDAQ: | 179.6 (Jun 2013) | 71.93 | 82.3 | 81.6 | 93.6 | 96.6 | 145.8 | 109.0 | 78.4 | |||
| 19 | 6 | NASDAQ: | 45.3 (Dec 2019) | 63.92 | 45.3 | 22.7 | 27.5 | 35.3 | 38.8 | 33.2 | 28.7 | |||
| 20 | 1 | NASDAQ: | 78.9 (Jul 2020) | 61.33 | 56.3 | 42.2 | 37.9 | 18.3 | 31.0 | 28.7 | 17.4 | |||
| 21 | 4 | 129.0 (Mar 2015) | 58.12 | 80.1 | 63.1 | 101.9 | 85.3 | 103.2 | 113.2 | 117.4 | ||||
| 22 | 2 | NASDAQ: | 61.5 (Dec 2019) | 56.78 | 61.5 | 52.9 | 40.2 | 45.6 | 47.8 | 37.5 | 34.3 | |||
| 23 | 1 | NASDAQ: | 56.0 (Jul 2019) | 53.51 | 48.2 | 44.1 | 40.2 | 39.4 | 35.4 | 28.6 | 25.7 | |||
| 24 | 2 | NASDAQ: | 61.4 (Aug 2015) | 52.52 | 41.2 | 40.3 | 40.4 | 39.3 | 56.5 | 42.0 | 27.4 | |||
| 25 | 3 | NASDAQ: | 111.7 (Mar 2015) | 38.66 | 54.7 | 63.5 | 67.4 | 61.6 | 68.3 | 79.7 | 66.1 | |||
| 26 | 2 | NASDAQ: | 47.0 (Jul 2015) | 33.52 | 24.3 | 21.7 | 26.7 | 27.4 | 43.1 | 36.7 | 26.0 | |||
| 27 | 3 | NASDAQ: | 38.2 (Oct 2020) | 34.44 | 19.5 | 13.8 | ||||||||
| 28 | 1 | 40.6 (Dec 2015) | 27.52 | 32.7 | 23.8 | 29.3 | 25.7 | 40.6 | 35.8 | 27.6 | ||||
| 29 | 4 | NASDAQ: | 25.9 (Nov 2020) | 25.53 | 14.5 | 10.6 | 10.8 | 10.8 | 8.8 | 3.8 | 2.6 | |||
| 30 | 1 | 37.3 (Dec 2016) | 19.93 | 21.5 | 23.0 | 24.5 | 37.3 | 28.8 | 30.2 | 28.7 | ||||
| 31 | [6] | 23.36 | 18.5 | 24.0 | 21.0 | 16.0 | - | |||||||
| 32 | 31.2 (Mar 2017) | 19.25 | 18.8 | 13.5 | 18.3 | 15.4 | 10.6 | 7.3 | 4.6 | |||||
| 33 | 24.0 (Jul 2015) | 16.03 | 15.2 | 15.1 | 18.3 | 20.4 | 13.8 | 12.9 | 10.8 | |||||
| 34 | 33.14 (Nov 2021) | 34.20 | 27.00 | 26.00 | 24.03 | 10.28 | 8.33 | 4.45 | 1.20 | |||||
| 35 | 1 | 44.07 | 62.52 | 19.62 | 7.68 | - | ||||||||
| 36 | 1 | 18.06 (Dec 2020) | 14.2 | 11.6 | 9.3 | 5.0 | 6.5 | 2.8 | 2.0 | - | ||||
| 37 | 1 | 10x Genomics[7] | 17.54 | 11.2 | - | |||||||||
| 38 | 1 | 41.17 | 59.98 | 93.42 | 60.85 | 30.53 | 30.54 | 16.79 | 15.10 | - | ||||
| 39 | 1 | 13.06 (Nov 2020) | 11.2 | - | ||||||||||
| 40 | 1 | 23.03 (2021) | 40.90 | 19.22 | - | |||||||||
| 41 | 1 | 18.50 (Dec 2021) | - | |||||||||||
| 42 | 1 | 27.15 (2021) | 19.01 | - | ||||||||||
| 43 | 1 | 15.29 (Nov 2021) | - | |||||||||||
| 44 | 1 | 10.94 (2021) | 11.75 | - | ||||||||||
| 45 | 1 | 10.21 (Dec 2021) | 10.19 | - |