This is a list of best-selling singles in Mexico, divided into the singles with the most certified units by the Asociación Mexicana de Productores de Fonogramas y Videogramas (AMPROFON), and the singles with the most claimed sales.
| Year | Artist(s) | Title | Certified units/sales | Certification[1] |
|---|---|---|---|---|
| 2019 | Karol G, Nicki Minaj | "Tusa" | 6,510,000 | 21× Diamond+3× Platinum+Gold |
| 2020 | Karol G | "Bichota" | 6,480,000 | 21× Diamond+3× Platinum |
| 2019 | Daddy Yankee | "Con Calma" | 3,360,000 | 11× Diamond+Platinum |
| 2012 | León Larregui | "Brillas" | 2,910,000 | 9× Diamond+3× Platinum+Gold |
| 2020 | Karol G | "Ay, Dios Mio!" | 2,790,000 | 9× Diamond+Platinum+Gold |
| 2016 | DJ Snake, Justin Bieber | "Let Me Love You" | 2,700,000 | 9× Diamond |
| 2021 | Imagine Dragons, JID | "Enemy" | 2,310,000 | 3× Diamond+Platinum+Gold |
| 2014 | J Balvin | "Ay Vamos" | 2,280,000 | 7× Diamond+3× Platinum |
| 2015 | "Ginza" | 2,070,000 | 6× Diamond+4× Platinum+Gold |
| Year | Artist(s) | Title | Certified units/sales | Certification | |
|---|---|---|---|---|---|
| 2021 | Karol G, Mariah Angeliq | "El Makinon" | 1,960,000 | 2× Diamond+4× Platinum | |
| 2013 | Enrique Iglesias, Marco Antonio Solís | "El Perdedor" | 1,860,000 | 6× Diamond+Platinum | |
| 2017 | Luis Fonsi, Daddy Yankee, Justin Bieber | "Despacito (remix)" | 1,770,000 | 5× Diamond+4× Platinum+Gold | |
| 2014 | Enrique Iglesias, Sean Paul, Descemer Bueno, Gente de Zona | "Bailando" | 1,710,000 | 5× Diamond+3× Platinum+Gold | |
| 2018 | Danna Paola | "Mala Fama" | 1,410,000 | 4× Diamond+3× Platinum+Gold | |
| 2021 | Justin Bieber, Daniel Caesar, Giveon | "Peaches" | 1,400,000 | 2× Diamond | |
| 2016 | León Larregui | "Locos" | 1,380,000 | 4× Diamond+3× Platinum | |
| 2020 | Maluma | "Hawái" | 1,290,000 | 4× Diamond+Platinum+Gold | |
| 2021 | J Balvin and María Becerra | "Qué más pues?" | 1,260,000 | Diamond+4× Platinum | |
| 2021 | Rauw Alejandro | "Todo de Ti" | 1,260,000 | Diamond+Gold | |
| 2020 | Olivia Rodrigo | "Drivers License" | 1,260,000 | Diamond+4× Platinum | |
| 2020 | Feid, Justin Quiles, J Balvin, Nicky Jam, Maluma, Sech | "Porfa (Remix)" | 1,200,000 | 4× Diamond | |
| 2015 | Natalia Lafourcade | "Hasta la Raíz" | 1,200,000 | 4× Diamond | |
| 2022 | Danny Ocean | "Fuera Del Mercado" | 1,050,000 | Diamond+2× Platinum+Gold | |
| 2020 | Olivia Rodrigo | "Deja Vu" | 1,050,000 | Diamond+2× Platinum+Gold |
| Year | Artist(s) | Title | Certified units/sales | Certification | |
|---|---|---|---|---|---|
| 2021 | Olivia Rodrigo | "Good 4 U" | 980,000 | Diamond+2× Platinum | |
| 2021 | Olivia Rodrigo | "Traitor" | 980,000 | ||
| 2021 | Gera MX, Christian Nodal | "Botella Tras Botella" | 910,000 | Diamond+Platinum+Gold | |
| 2021 | Sebastián Yatra, Myke Towers | "Pareja del Año" | |||
| 2021 | Karol G, Anuel AA, J Balvin | "Location" | |||
| 2021 | Acraze, Cherish | "Do It to It" | |||
| 2019 | Karol G | "Ocean" | 870,000 | 2× Diamond+4× Platinum+Gold | |
| 2022 | Shakira and Rauw Alejandro | "Te Felicito" | 840,000 | Diamond + Platinum | |
| 2016 | Billie Eilish | "Ocean Eyes" | 840,000 | 2× Diamond+4× Platinum | |
| 2015 | Maluma | "Borró Cassette" | 840,000 | ||
| 2021 | Natanael Cano, Oscar Maydon | "Porte Exuberante" | 770,000 | Diamond+Gold | |
| 2019 | Maluma | "11 PM" | 720,000 | 2× Diamond+2× Platinum | |
| 2020 | Christian Nodal, Ángela Aguilar | "Dime Cómo Quieres" | 700,000 | Diamond | |
| 2022 | Imagine Dragons | "Bones" | |||
| 2022 | Junior H, Luis R. Conriquez | "Los Botones Azules" | |||
| 2022 | Rosalía | "Despechá" | |||
| 2016 | Shakira and Carlos Vives | "La Bicicleta" | 690,000 | 2× Diamond+Platinum+ Gold | |
| 2020 | Shakira and Black Eyed Peas | "Girl Like Me" | 630,000 | 4× Platinum+Gold | |
| 2021 | Anitta | "Envolver" | |||
| 2022 | Becky G and Karol G | "Mamiii" | |||
| 2022 | Harry Styles | "As It Was" | |||
| 2020 | Black Eyed Peas and Shakira | "Girl Like Me" | |||
| 2019 | Maluma | "HP" | 630,000 | 2× Diamond+Gold | |
| 2016 | Shakira and Maluma | "Chantaje" | 600,000 | 2× Diamond | |
| 2014 | Sia | "Chandelier" | 600,000 | 2× Diamond |
| Year | Artist | Title | Sales | ||
|---|---|---|---|---|---|
| 1950 | Pedro Infante | "Las Mañanitas" | 15,000,000 | [2] | |
| 1969 | Julio Jaramillo | "Ay Mexicanita" | 2,000,000 | [3] | |
| 1980 | Lipps Inc. | "Funkytown" | 1,000,000 | [4] | |
| 1980 | Lipps Inc. | "How Long" | 1,000,000 | ||
| 1979 | Lipps Inc. | "Rock It" | 1,000,000 | ||
| 1954 | Vicente Garrido Calderón | "No me platiques más" | 1,000,000 | [5] | |
| 1973 | Angélica María | "Tú sigues siendo el mismo" | 1,000,000 | [6] | |
| 1978 | Boney M. | "Rivers of Babylon" | 1,000,000 | [7] | |
| 1989 | Kaoma | "Lambada" | 750,000 | [8] | |
| 1979 | ABBA | "Chiquitita" | 500,000 | [9] | |
| Ángela Carrasco | "Quererte a Ti" | 500,000 | [10] |