List of androgens/anabolic steroids (alternate) explained
This is a list of androgens/anabolic steroids (AAS) or testosterone derivatives. Esters are mostly not included in this list; for esters, see here instead. The major classes of testosterone derivatives include the following (as well as combinations thereof):
- Testosterone derivatives: immediate derivatives of testosterone not falling into the groups below
- 4,5α-Reduced/dihydrogenated testosterone derivatives: dihydrotestosterone (DHT) derivatives
- 19-Demethylated testosterone derivatives: 19-nortestosterone (nandrolone) derivatives
- 17α-Alkylated testosterone derivatives: methyltestosterone and ethyltestosterone derivatives
- 17α-Ethenylated/ethynylated testosterone derivatives: ethynyltestosterone (ethisterone) and vinyltestosterone derivatives
The last group consists of progestins with mostly only very weak androgenic/anabolic activity.
AAS that are listed as marketed may be marketed as one or more esters rather than as the listed AAS itself.
This list specifically pertains to steroidal androgens; nonsteroidal androgens like the selective androgen receptor modulators (SARMs) andarine and enobosarm (ostarine) are not included here.
Natural/endogenous
- Marketed
- Androstenediol (A5; 5-androstenediol)
- Boldenone (δ1-T)*
- Dehydroepiandrosterone (DHEA; prasterone, 5-androstenolone)
- Dihydrotestosterone (DHT; androstanolone, stanolone)
- Nandrolone (19-NT; 19-nortestosterone)*
- Testosterone (T; 4-androstenolone)
- Never marketed
* Only present endogenously in trace/very small amounts or present in other species.
Synthetic
Testosterone derivatives
- Non-17α-alkylated derivatives
- 17α-Alkylated derivatives
Dihydrotestosterone derivatives
- Non-17α-alkylated derivatives
- Marketed
- Never marketed
- 1-Testosterone (dihydroboldenone; δ1-DHT)
- Mesabolone (a 17-ether prodrug of δ1-DHT)
- Prostanozol (a 17-ether prodrug of 17α-demethylstanozolol)
- 17α-Alkylated derivatives
- Marketed
- Androisoxazole (an isoxazole A ring-fused derivative of 17α-methyl-DHT)
- Furazabol (a furan A ring-fused derivative of 17α-methyl-DHT)
- Mebolazine (an azine dimer prodrug of methasterone)
- Mestanolone (17α-methyl-DHT)
- Oxandrolone (2-oxa-17α-methyl-DHT)
- Oxymetholone (2-hydroxymethylene-17α-methyl-DHT)
- Stanozolol (a pyrazole A ring-fused derivative of 17α-methyl-DHT)
- Never marketed
19-Nortestosterone derivatives
- Non-17α-alkylated derivatives
- 17α-Alkylated derivatives
Other testosterone derivatives
- 17α-Alkenylated derivatives
- 17α-Alkynylated derivatives
See also
Further reading
- Kicman . A T . Pharmacology of anabolic steroids . British Journal of Pharmacology . 154 . 3 . 2008 . 502–521 . 0007-1188 . 10.1038/bjp.2008.165 . 18500378 . 2439524.
- Fragkaki AG, Angelis YS, Koupparis M, Tsantili-Kakoulidou A, Kokotos G, Georgakopoulos C . Structural characteristics of anabolic androgenic steroids contributing to binding to the androgen receptor and to their anabolic and androgenic activities. Applied modifications in the steroidal structure . Steroids . 74 . 2 . 172–97 . 2009 . 19028512 . 10.1016/j.steroids.2008.10.016 . 41356223 .
- McRobb L, Handelsman DJ, Kazlauskas R, Wilkinson S, McLeod MD, Heather AK . Structure-activity relationships of synthetic progestins in a yeast-based in vitro androgen bioassay . J. Steroid Biochem. Mol. Biol. . 110 . 1–2 . 39–47 . 2008 . 18395441 . 10.1016/j.jsbmb.2007.10.008 . 5612000 .