These hits topped the Ultratop 50 in 2006.[1]
| Issue Date | Artist | Song | |
|---|---|---|---|
| January 7 | Kippensoep All Stars | Kippensoep voor iedereen (Chicken Soup For Everyone) | |
| January 14 | Udo | Isn't it time | |
| January 21 | Udo | Isn't it time | |
| January 28 | Udo | Isn't it time | |
| February 4 | Udo | Isn't it time | |
| February 11 | Udo | Isn't it time | |
| February 18 | Udo | Isn't it time | |
| February 25 | El mundo bailando | ||
| March 4 | Belle Perez | El mundo bailando | |
| March 11 | Belle Perez | El mundo bailando | |
| March 18 | Je t'adore (I Adore You) | ||
| March 25 | Kate Ryan | Je t'adore | |
| April 1 | Kate Ryan | Je t'adore | |
| April 8 | Kate Ryan | Je t'adore | |
| April 15 | Kate Ryan | Je t'adore | |
| April 22 | The Pussycat Dolls featuring will.i.am | Beep | |
| April 29 | Pump It | ||
| May 6 | Hips Don't Lie | ||
| May 13 | Shakira featuring Wyclef Jean | Hips Don't Lie | |
| May 20 | Rood (Red) | ||
| May 27 | Marco Borsato | Rood | |
| June 3 | Marco Borsato | Rood | |
| June 10 | Marco Borsato | Rood | |
| June 17 | Marco Borsato | Rood | |
| June 24 | Marco Borsato | Rood | |
| July 1 | Marco Borsato | Rood | |
| July 8 | Laura Lynn | Jij bent de mooiste (You Are the Most Beautiful) | |
| July 15 | Laura Lynn | Jij bent de mooiste | |
| July 22 | Laura Lynn | Jij bent de mooiste | |
| July 29 | Marco Borsato | Rood | |
| August 5 | Marco Borsato | Rood | |
| August 12 | Henkie | Lief klein konijntje (Cute Little Bunny) | |
| August 19 | Henkie | Lief klein konijntje | |
| August 26 | Henkie | Lief klein konijntje | |
| September 2 | Henkie | Lief klein konijntje | |
| September 9 | Henkie | Lief klein konijntje | |
| September 16 | Henkie | Lief klein konijntje | |
| September 23 | Rock This Party (Everybody Dance Now) | ||
| September 30 | Bob Sinclar, Cutee-B, Dollarman and Big Ali | Rock This Party (Everybody Dance Now) | |
| October 7 | Bob Sinclar, Cutee-B, Dollarman and Big Ali | Rock This Party (Everybody Dance Now) | |
| October 14 | Bob Sinclar, Cutee-B, Dollarman and Big Ali | Rock This Party (Everybody Dance Now) | |
| October 21 | I Don't Feel Like Dancin' | ||
| October 28 | Scissor Sisters | I Don't Feel Like Dancin | |
| November 4 | Scissor Sisters | I Don't Feel Like Dancin | |
| November 11 | Scissor Sisters | I Don't Feel Like Dancin | |
| November 18 | Scissor Sisters | I Don't Feel Like Dancin | |
| November 25 | Scissor Sisters | I Don't Feel Like Dancin | |
| December 2 | Scissor Sisters | I Don't Feel Like Dancin | |
| December 9 | Vonken en vuur (Sparks and Fire) | ||
| December 16 | Clouseau | Vonken en vuur | |
| December 23 | Clouseau | Vonken en vuur | |
| December 30 | Clouseau | Vonken en vuur |