This is the list of the number-one albums of the UK Indie Breakers Chart during the 2000s.
| nth album to top the UK Independent Album Breakers Chart | |||
| scope=row style="text-align:center;" | re | Return of an album to number one |
|---|
| scope=col | scope=col | Artist | scope=col | Album | scope=col | Record label | scope=col | Reached number one | scope=col | Weeks at number one | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| scope=row style="text-align:center;" colspan=6 | |||||||||||
| scope=row style="text-align:center;" | 1 | Friendly Fires | Friendly Fires | XL | 2 | ||||||
| scope=row style="text-align:center;" | 2 | Duckworth Lewis | Divine Comedy | 1 | |||||||
| scope=row style="text-align:center;" | Friendly Fires | Friendly Fires | XL | 4 | |||||||
| scope=row style="text-align:center;" | 3 | Conditions | Infectious | 1 | |||||||
| scope=row style="text-align:center;" | 4 | xx | Young Turks | 2 | |||||||
| scope=row style="text-align:center;" | Friendly Fires | Friendly Fires | XL | 3 | |||||||
| scope=row style="text-align:center;" | 5 | Monsters of Folk | Monsters of Folk | Rough Trade | 1 | ||||||
| scope=row style="text-align:center;" | xx | Young Turks | 1 | ||||||||
| scope=row style="text-align:center;" | 6 | Don't Look Down | Rainbow City | 1 | |||||||
| scope=row style="text-align:center;" | 7 | Sub Focus | Sub Focus | Ram Records | 2 | ||||||
| scope=row style="text-align:center;" | 8 | Pink Martini | Splendor in the Grass | Wrasse | 1 | ||||||
| scope=row style="text-align:center;" | 9 | Phrazes for the Young | Rough Trade | 1 | |||||||
| scope=row style="text-align:center;" | 10 | Flight of the Conchords | I Told You I Was Freaky | Sub Pop | 1 | ||||||
| scope=row style="text-align:center;" | 11 | 4AD | 2 | ||||||||
| scope=row style="text-align:center;" | 12 | Red Revelations | Hump Head | 1 | |||||||
| scope=row style="text-align:center;" | xx | Young Turks | 3 |