| Caption: | Standard U.S. Highway shields |
| Statehwy: | Route X |
| Interstate: | Route I-X or Route X |
| Us: | Route US X or Route X |
| Notes: | Routes are not always state-maintained, and not all state highways are Routes. |
| Links: | MA |
| Map Custom: | yes |
| Map Notes: | U.S. Highways highlighted in red |
The U.S. Highways in Massachusetts comprise eight current U.S. Highways and one former route.