This is a list of the Spanish PROMUSICAE Top 20 Singles number-ones of 1988.[1]
| Issue Date | Song | Artist |
|---|---|---|
| 7 January | "Never Gonna Give You Up" | Rick Astley |
| 14 January | "Never Can Say Goodbye" | The Communards |
| 21 January | ||
| 28 January | ||
| 4 February | "Never Gonna Give You Up" | Rick Astley |
| 11 February | "Always on My Mind" | Pet Shop Boys |
| 18 February | ||
| 25 February | ||
| 3 March | ||
| 10 March | "Together Forever" | Rick Astley |
| 17 March | "Always on My Mind" | Pet Shop Boys |
| 24 March | ||
| 31 March | ||
| 7 April | ||
| 14 April | "Together Forever" | Rick Astley |
| 21 April | ||
| 28 April | "Always on My Mind" | Pet Shop Boys |
| 5 May | ||
| 12 May | ||
| 19 May | "Eloise" | Tino Casal |
| 26 May | ||
| 2 June | "Gimme Hope Jo'anna" | Eddy Grant |
| 9 June | ||
| 16 June | "Eloise" | Tino Casal |
| 23 June | "Gimme Hope Jo'anna" | Eddy Grant |
| 30 June | ||
| 7 July | ||
| 14 July | ||
| 21 July | ||
| 28 July | ||
| 4 August | ||
| 11 August | ||
| 18 August | ||
| 25 August | ||
| 1 September | ||
| 8 September | ||
| 15 September | "Im Nin'alu" | Ofra Haza |
| 22 September | "Perfect" | Fairground Attraction |
| 29 September | "Yé ké yé ké" | Mory Kanté |
| 3 October | "Desire" | U2 |
| 10 October | ||
| 17 October | "Im Nin'alu" | Ofra Haza |
| 24 October | "Domino Dancing" | Pet Shop Boys |
| 31 October | "Girl You Know It's True" | Milli Vanilli |
| 7 November | ||
| 14 November | ||
| 21 November | "Nothing's Gonna Change My Love For You" | Glenn Medeiros |
| 28 November | ||
| 5 December | ||
| 12 December | ||
| 19 December | ||
| 26 December |