List of Schedule II controlled substances (U.S.) explained

This is the list of Schedule II controlled substances in the United States as defined by the Controlled Substances Act.^[1] The following findings are required for substances to be placed in this schedule:^[2]

1. The drug or other substance has a high potential for abuse.
2. The drug or other substance has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions.
3. Abuse of the drug or other substances may lead to severe psychological or physical dependence.

The complete list of Schedule II substances is as follows. The Administrative Controlled Substances Code Number and Federal Register citation for each substance is included.

Drugs

	Class	Drug
9050	opiate	Codeine^[3]
9334	opiate	Dihydroetorphine^[4]
9190	opiate	Ethylmorphine
9059	opiate	Etorphine hydrochloride^[5]
9640	opiate	Granulated opium
9193	opiate	Hydrocodone
9150	opiate	Hydromorphone
9260	opiate	Metopon
9300	opiate	Morphine
9668	opiate	Noroxymorphone^[6]
9610	opiate	Opium extracts
9620	opiate	Opium fluid
9330	opiate	Oripavine^[7]
9143	opiate	Oxycodone
9652	opiate	Oxymorphone
9639	opiate	Powdered opium
9600	opiate	Raw opium
9333	opiate	Thebaine
9630	opiate	Tincture of opium
	opiate	Opium poppy and poppy straw^[8]
9040	stimulant	Coca, leaves and any salt, compound, derivative or preparation of coca leaves
9041	stimulant	Cocaine, and its salts, isomers, derivatives and salts of isomers and derivatives
9180	stimulant	Ecgonine, and its salts, isomers, derivatives and salts of isomers and derivatives
9670	opiate	Concentrate of poppy straw (the crude extract of poppy straw in either liquid, solid or powder form which contains the phenanthrene alkaloids of the opium poppy)^[9]
9737	opiate	Alfentanil^[10]
9010	opiate	Alphaprodine
9020	opiate	Anileridine
9800	opiate	Bezitramide
9273	opiate	Bulk dextropropoxyphene (non-dosage forms)^[11]
9743	opiate	Carfentanil^[12]
9120	opiate	Dihydrocodeine
9170	opiate	Diphenoxylate
9801	opiate	Fentanyl
9226	opiate	Isomethadone
9648	opiate	Levo-alphacetylmethadol^[13]
9210	opiate	Levomethorphan
9220	opiate	Levorphanol
9240	opiate	Metazocine
9250	opiate	Methadone
9254	opiate	Methadone intermediate
9802	opiate	Moramide intermediate
9245	opiate	Oliceridine^[14]
9230	opiate	Pethidine (meperidine)
9232	opiate	Pethidine intermediate A
9233	opiate	Pethidine intermediate B
9234	opiate	Pethidine intermediate C
9715	opiate	Phenazocine
9730	opiate	Piminodine
9732	opiate	Racemethorphan
9733	opiate	Racemorphan
9739	opiate	Remifentanil^[15]
9740	opiate	Sufentanil^[16]
9780	opiate	Tapentadol^[17]
9729	opiate	Thiafentanil^[18]
1100	stimulant	Amphetamine, its salts, optical isomers, and salts of its optical isomers^[19]
1105	stimulant	Methamphetamine, its salts, optical isomers, and salts of optical isomers
1631	stimulant	Phenmetrazine and its salts ^[20]
1724	stimulant	Methylphenidate
1205	stimulant	Lisdexamfetamine, its salts, isomers, and salts of its isomers^[21]
2125	depressant	Amobarbital^[22]
2550	depressant	Glutethimide^[23]
2270	depressant	Pentobarbital
7471	depressant	Phencyclidine^[24]
2315	depressant	Secobarbital
7379	hallucinogen	Nabilone^[25]
7365	hallucinogen	Dronabinol oral solution^[26]
8501	precursor	Phenylacetone^[27]
7460	precursor	1-phenylcyclohexylamine
8603	precursor	1-piperidinocyclohexanecarbonitrile (PCC)
8333	precursor	4-anilino-N-phenethyl-4-piperidine (4-ANPP)^[28]
8366	precursor	Norfentanyl^[29]

See also

• List of Schedule I controlled substances (U.S.)
• List of Schedule III controlled substances (U.S.)
• List of Schedule IV controlled substances (U.S.)
• List of Schedule V controlled substances (U.S.)

Notes and References

1. Web site: 21 C.F.R. 1308.12 (Schedule II) . September 7, 2023 . Code of Federal Regulations.
2. retrieved October 7, 2007
3. Web site: Ingersoll . John . September 29, 1971 . Schedules of Controlled Substances: Removal of Naloxone From Control . https://web.archive.org/web/20210916175305/https://isomerdesign.com/Cdsa/FR/36FR19116.pdf . September 16, 2021 . September 7, 2023 . Isomer Design . Bureau of Narcotics and Dangerous Drugs.
4. Web site: Mercado . Julio . November 17, 2000 . Schedule II Control of Dihydroetorphine Under the Controlled Substances Act . September 7, 2023 . . Drug Enforcement Administration.
5. Web site: Bartels, Jr. . John R. . March 29, 1974 . Etorphine Hydrochloride Transfer to Schedule II . https://web.archive.org/web/20210926010118/https://isomerdesign.com/Cdsa/FR/39FR11535.pdf . September 26, 2021 . September 7, 2023 . Isomer Design . Drug Enforcement Administration.
6. Web site: Dhillon . Uttam . August 16, 2019 . Listing of Noroxymorphone in the Code of Federal Regulations and Assignment of a Controlled Substances Code Number . September 7, 2023 . . Drug Enforcement Administration.
7. Web site: Leonhart . Michele . September 24, 2007 . Designation of Oripavine as a Basic Class of Controlled Substance . September 7, 2023 . . Drug Enforcement Administration.
8. Web site: Bartels Jr. . John R. . June 20, 1974 . PART 1308— SCHEDULES OF CONTROLLED SUBSTANCES: Annual Publication . https://web.archive.org/web/20230906194000/https://archives.federalregister.gov/issue_slice/1974/6/20/22139-22143.pdf . September 6, 2023 . September 6, 2023 . . Drug Enforcement Administration.
9. Web site: Bartels, Jr. . John R. . February 14, 1975 . Concentrate of Poppy Straw, Addition to Schedule II and Authorizing its Importation . https://web.archive.org/web/20210926002647/https://isomerdesign.com/Cdsa/FR/40FR6779.pdf . September 26, 2021 . September 7, 2023 . Isomer Design . Drug Enforcement Administration.
10. Web site: Lawn . John . January 23, 1987 . Rescheduling of Alfentanil from Schedule I to Schedule II . https://web.archive.org/web/20190728013952/https://isomerdesign.com/Cdsa/FR/52FR2516.pdf . July 28, 2019 . September 7, 2023 . Isomer Design . Drug Enforcement Administration.
11. Web site: Bensinger . Peter . July 22, 1980 . Control of Bulk Dextropropoxyphene (Non-dosage Forms) in Schedule II as an Opiate . https://web.archive.org/web/20160324042500/https://isomerdesign.com/Cdsa/FR/45FR48881.pdf . March 24, 2016 . September 7, 2023 . Isomer Design . Drug Enforcement Administration.
12. Web site: Lawn . John . October 28, 1988 . Placement of Carfentanil into Schedule II . https://web.archive.org/web/20160322221649/https://isomerdesign.com/Cdsa/FR/53FR43684.pdf . March 22, 2016 . September 7, 2023 . Isomer Design . Drug Enforcement Administration.
13. Web site: Bonner . Robert . August 18, 1993 . Schedules of Controlled Substances; Transfer of Levo-acetylmethadol from Schedule I into Schedule II . https://web.archive.org/web/20190728014110/http://isomerdesign.com/Cdsa/FR/58FR43795.pdf . July 28, 2019 . January 16, 2023 . Isomer Design . Drug Enforcement Administration.
14. Web site: Evans . D. Christopher . July 12, 2021 . Schedules of Controlled Substances: Placement of Oliceridine in Schedule II . September 7, 2023 . . Drug Enforcement Administration.
15. Web site: Milford, Jr. . James S. . November 5, 1996 . Schedules of Controlled Substances: Placement of Remifentanil Into Schedule II . January 16, 2023 . . Drug Enforcement Administration.
16. Web site: Mullen, Jr. . Francis M. . May 25, 1984 . Schedules of Controlled Substances; Rescheduling of Sufentanil into Schedule II . live . https://web.archive.org/web/20190519024955/http://isomerdesign.com/Cdsa/FR/49FR22074.pdf . May 19, 2019 . January 16, 2023 . Isomer Design . Drug Enforcement Administration.
17. Web site: Leonhart . Michele . May 21, 2009 . Schedules of Controlled Substances: Placement of Tapentadol Into Schedule II . January 16, 2023 . . Drug Enforcement Administration.
18. Web site: Dhillon . Uttam . June 10, 2019 . Schedules of Controlled Substances: Placement of Thiafentanil in Schedule II . September 7, 2023 . . Drug Enforcement Administration.
19. Web site: Ingersoll . John . July 7, 1971 . Amphetamine, Methamphetamine, and Optical Isomers . live . https://web.archive.org/web/20220303023154/http://isomerdesign.com/Cdsa/FR/36FR12734.pdf . March 3, 2022 . January 16, 2023 . Isomer Design . Bureau of Narcotics and Dangerous Drugs.
20. Web site: Finlator . John . October 28, 1971 . Phenmetrazine and its salts, and Methylphenidate . live . https://web.archive.org/web/20220303023153/http://isomerdesign.com/Cdsa/FR/36FR20686.pdf . March 3, 2022 . January 16, 2023 . Isomer Design . Bureau of Narcotics and Dangerous Drugs.
21. Web site: Leonhart . Michele . May 3, 2007 . Schedules of Controlled Substances: Placement of Lisdexamfetamine Into Schedule II . live . https://archive.today/20230116081337/https://www.federalregister.gov/documents/2007/05/03/E7-8421/schedules-of-controlled-substances-placement-of-lisdexamfetamine-into-schedule-ii . January 16, 2023 . January 16, 2023 . . Drug Enforcement Administration.
22. Web site: Bartels, Jr. . John R. . November 13, 1973 . Schedule II Control of Amobarbital, Pentobarbital, Secobarbital, and their salts . live . https://web.archive.org/web/20220303023142/http://isomerdesign.com/Cdsa/FR/38FR31310.pdf . March 3, 2022 . January 16, 2023 . Isomer Design . Drug Enforcement Administration.
23. Web site: Bonner . Robert . March 21, 1991 . Schedules of Controlled Substances: Transfer of Glutethimide from Schedule III to Schedule II . live . https://web.archive.org/web/20220303023106/http://isomerdesign.com/Cdsa/FR/56FR11930.pdf . March 3, 2022 . January 16, 2023 . Isomer Design . Drug Enforcement Administration.
24. Web site: Bensinger . Peter . January 25, 1978 . Placement of Phencyclidine in Schedule II . live . https://web.archive.org/web/20220303023116/http://isomerdesign.com/Cdsa/FR/43FR3359.pdf . March 3, 2022 . January 16, 2023 . Isomer Design . Drug Enforcement Administration.
25. Web site: Lawn . John . April 7, 1987 . Placement of Nabilone in Schedule II . https://web.archive.org/web/20230430024311/https://www.govinfo.gov/content/pkg/FR-1987-04-07/pdf/FR-1987-04-07.pdf . April 30, 2023 . September 7, 2023 . . . 11042.
26. Web site: Patterson . Robert . November 22, 2017 . Schedules of Controlled Substances: Placement of FDA-Approved Products of Oral Solutions Containing Dronabinol [(-)-delta-9-trans-tetrahydrocannabinol (delta-9-THC)] in Schedule II ]. September 7, 2023 . . Drug Enforcement Administration.
27. Web site: Bensinger . Peter . February 11, 1980 . Schedules of Controlled Substances; Schedule II Placement of Phenylacetone; (Phenyl-2-propanone, P2P, methyl benzyl ketone, benzyl methyl ketone) . live . https://web.archive.org/web/20220303023127/http://isomerdesign.com/Cdsa/FR/44FR71822.pdf . March 3, 2022 . January 16, 2023 . Isomer Design . Drug Enforcement Administration.
28. Web site: Leonhart . Michele . June 29, 2010 . Control of Immediate Precursor Used in the Illicit Manufacture of Fentanyl as a Schedule II Controlled Substance . live . https://archive.today/20230116080523/https://www.federalregister.gov/documents/2010/06/29/2010-15520/control-of-immediate-precursor-used-in-the-illicit-manufacture-of-fentanyl-as-a-schedule-ii . January 16, 2023 . January 16, 2023 . Federal Register . Drug Enforcement Administration.
29. Web site: Dhillon . Uttam . April 17, 2020 . Control of the Immediate Precursor Norfentanyl Used in the Illicit Manufacture of Fentanyl as a Schedule II Controlled Substance . September 7, 2023 . . Drug Enforcement Administration.