This is a list of cast members from the former ABC daytime soap opera, Port Charles.
| Actor | Character | Duration | |
|---|---|---|---|
| Bennett Devlin | 1997–98 | ||
| Courtney Kanelos | 1998–2000 | ||
| Ed Grant | 2001–03 | ||
| Alex Garcia | 1997–99 | ||
| 1997–99 | |||
| Matt Amshey | Michael Pomerantz | 1999–2000 | |
| Opal Anchel | Arianna Shapour | 2001 | |
| Izzy Assencos | Jamal Woods | 2002 | |
| Maurice Benard | Sonny Corinthos | 2000 | |
| Joy Bisco | Casey Leong | 2002–03 | |
| Marissa Leong | 2002–03 | ||
| 2001–02 | |||
| Paige Smith | 2002 | ||
| Rebecca Barrington | 2002 | ||
| 1999–2002 | |||
| 1997–2003 | |||
| Joshua Temple | 2002–03 | ||
| 1997–2001 | |||
| Maree Cheatham | Charlene Simpson | 1999 | |
| Nurse Mary Scanlon Collins | 1997–2003 | ||
| 1997–2001 | |||
| Shell Danielson | Dominique Stanton | 1997–99 | |
| Linda Dano | Rae Cummings | 2000 | |
| Tamara Davies | Amy Harris | 2002 | |
| William deVry | Tim Dolan | 2002 | |
| Joe Scanlon | 1997–99 | ||
| Caleb Morley | 2001–03 | ||
| Michael Morley | 2001 | ||
| 2002–03 | |||
| Kiko Ellsworth | Jamal Woods | 2000–03 | |
| Stephanie Erb | Camille Owens | 2000 | |
| Mary Beth Evans | Katherine Bell | 1997–99 | |
| Tori Falcon | Alison Hebrart | 2003 | |
| Joe Scanlon | 1999–2000 | ||
| 2001–03 | |||
| 1998 | |||
| Nancy Lee Grahn | Alexis Davis | 2000 | |
| 1997 | |||
| Julie Devlin | 1997–2001 | ||
| Ron Hale | Mike Corbin | 1997–2000 | |
| Karen Wexler | 1997–99 | ||
| 1997–2002 | |||
| Susan Haskell | Granya Thornhart | 2001 | |
| 1997–2003 | |||
| Jake Marshak | 1997–98 | ||
| David Holcomb | Greg Cooper | 1997–2000 | |
| Lark Madison-Scanlon | 1997–99 | ||
| Anders Hove | Cesar Faison | 2000 | |
| Colton James | Neil Kanelos | 1998–2000 | |
| Ian Thornhart | 2000–03 | ||
| Imani | 2003 | ||
| 1997–2003 | |||
| Ryan Chamberlain | 1998 | ||
| Matt Harmon | 1997–2000 | ||
| Ricky Garza | 2001–03 | ||
| Brad Maule | Tony Jones | 1997, 1999–2000 | |
| Robin Scorpio | 1998 | ||
| Alex Mendoza | Joe Scanlon | 2000–02 | |
| Livvie Locke | 2000–03 | ||
| Tess Ramsey | 2002–03 | ||
| Ellen Burgess | 1997–98 | ||
| Laura Nevell | Brenda Madison | 2002–03 | |
| Stephen Nichols | Stefan Cassadine | 1997 | |
| Chris Ramsey | 1997–2003 | ||
| Wayne Northrop | Rex Stanton | 1997–98 | |
| Gabriela Garza | 2000–02 | ||
| Kay Panabaker | Sara | 2002 | |
| Frank Scanlon | 1997–2003 | ||
| 1997–2002 | |||
| 2000–03 | |||
| 2000–03 | |||
| 1997–2003 | |||
| Ellen Burgess | 1998–99 | ||
| 1997–2003 | |||
| Colleen Russo | 2000–03 | ||
| 1997–2003 | |||
| Sally Spaide | Doreen Luccio | 2002–03 | |
| Elizabeth Barrington | 2002–03 | ||
| 2002–03 | |||
| Sebastian Dupree | 1999 | ||
| Alex Garcia | 1999–2001 | ||
| 1999–2003 | |||
| 1997–2001 |