There are 16 National Natural Landmarks in Missouri.
| Name | Image | Date | Location | County | Ownership | Description |
|---|---|---|---|---|---|---|
| East Prairie 36.655°N -89.3283°W | state | A rare untouched wet-mesic bottomland hardwood forest in the Mississippi Alluvial Plain, it is the home of several state and national champion trees | ||||
| private | Contains a dendritic system of subsurface karst streams and tributaries. | |||||
| federal | One of the most ancient sinkhole ponds in the Ozark plateaus. Located in Mark Twain National Forest. | |||||
| Golden City 37.3626°N -94.1502°W | Barton | private | An unplowed remnant of the tall grass prairie ecosystem. | |||
| Thayer 36.5243°N -91.5439°W | state | An excellent example of karst topography, this canyon is a collapsed dolomite cave with a 200feet natural bridge. Water in this canyon emerges 9miles away in Mammoth Spring, Arkansas. | ||||
| 36.7867°N -91.3475°W | private | Spring in the Ozarks that discharges into a high quality, cascading stream. | ||||
| state | Contains a nearly virgin sugar maple and mockernut hickory forest. | |||||
| St. James 37.9553°N -91.5363°W | private | A natural spring, the fifth largest in the state. It has a notable trout park and a historic iron works in a privately owned park. | ||||
| 39.6886°N -91.3315°W | private | Exceptionally good examples of the maze type of cavern development. | ||||
| 36.6675°N -93.3397°W | private | Includes one of the greatest dripstone units of all the Ozark caves. | ||||
| 38.0608°N -91.2272°W | state | Contains an unusually large and varied number of speleothems. | ||||
| state | Contains one of the finest Pleistocene relict habitats in Missouri. | |||||
| state | One of the largest remaining virgin tall grass prairies. | |||||
| private | A virgin tall grass prairie occurring within the transition zone between the oak-hickory forest and typical tall grass prairie. | |||||
| private | Contains the most diverse fauna known for any cave west of the Mississippi River. | |||||
| private | An essentially virgin oak-hickory-dominated forest in a condition of gradual change to a sugar maple-dominated forest. | |||||