The minister of regional development and local governments of Latvia was a member of the Cabinet of Ministers of Latvia, and the political leader of the Ministry of Regional Development and Local Governments of Latvia. In 2002, the office was split from the office of the Minister of Environment, and since 2011, merged again.
| Name | Took office | Left office | Party | ||
| 1 | Ivars Gaters | 7 November 2002 | 9 March 2004 | New Era Party | |
| 2 | Andrejs Radzevičs | 9 March 2004 | 2 December 2004 | without party | |
| 3 | Māris Kučinskis | 2 December 2004 | 7 November 2006 | People's Party | |
| 4 | Aigars Štokenbergs | 7 November 2006 | 19 October 2007 | People's Party | |
| 5 | Edgars Zalāns | 8 November 2007 | 17 March 2010 | People's Party | |
| 6 | Dagnija Staķe | 13 May 2010 | 3 November 2010 | Union of Greens and Farmers | |
| 7 | Valdis Dombrovskis | 3 November 2010 | 31 December 2010 | New Era Party |