The following lists Michigan State Historic Sites in St. Clair County, Michigan, United States. Sites marked with a dagger (†) are also listed on the National Register of Historic Places in St. Clair County, Michigan. Those with a double dagger (‡) are also designated National Historic Landmarks.__TOC__
| width="30%" | Name | Image | Location | width="125px" H | City | width="125px" | Listing date | ||
|---|---|---|---|---|---|---|---|---|---|
| Algonac City Hall (Demolished) | 1410 St. Clair River Drive | Algonac | |||||||
| Almont New Church (Swedenborgian) | Northeast corner of Cameron and Tubspring roads | Allenton vicinity | |||||||
| 1240 St. Clair River Drive | Algonac | ||||||||
| Cole Class - West Brockway Methodist Church Informational Designation | 7015 Carson Road, NE corner of Wilkes Road | Yale vicinity | |||||||
| Colony Tower† | 6503 Dyke Road | Clay Township | |||||||
| Congregational Church | 300 Adams St | St. Clair | |||||||
| David and Laura Lester House | 406 S. Main Street | Marine City | 2008 | ||||||
| James A. Davidson House | 1229 Seventh Street | Port Huron | |||||||
| Wilbur F. Davidson House† | 1707 Military Street | Port Huron | |||||||
| East China Fractional District No. 2 School | 696 Meisner Road | East China Township | |||||||
| Tom Edison at Grand Trunk Informational Designation (site of the Grand Trunk Western Railroad Depot†) | Thomas Edison Depot Museum, 510 Edison Parkway | Port Huron | |||||||
| First Baptist Church (Demolished) | Erie Square | Port Huron | |||||||
| First Baptist Church | 308 South Fourth Street | St. Clair | |||||||
| Fort Gratiot† | 520 State Street | Port Huron | |||||||
| Fort Gratiot Lighthouse† | Omar and Garfield streets | Port Huron | |||||||
| Fort Sinclair (20SC58) | South of the mouth of the Pine River on the St. Clair River | St. Clair | |||||||
| Fort St. Joseph | Gratiot Park on M-25 (Gratiot Avenue) and Forest Street, under the Bluewater Bridge | Port Huron | |||||||
| Grace Episcopal Church | 1213 Sixth Street | Port Huron | |||||||
| Gratiot Park United Methodist Church | 2503 Cherry Street | Port Huron | |||||||
| Graziadei-Casello Building | 307 Huron Avenue | Port Huron | |||||||
| Greenwood Cemetery | 444 Pleasant Street | Marine City | 1996 | ||||||
| Harrington Hotel† | 1026 Military Street | Port Huron | |||||||
| Harsen House | 2006 Golf Course Road | Harsens Island | |||||||
| Holy Cross Parish | 618 South Water Street, SE corner of Bridge Street | Marine City | |||||||
| Immaculate Conception of Blessed Virgin Mary | 9764 Dixie Hwy | Ira Township | 2018 | ||||||
| Jefferson Sheldon House | 807 Prospect Place | Port Huron | |||||||
| Ladies of the Maccabees Building† | 901 Huron Avenue | Port Huron | |||||||
| Lightship No. 103‡ | Pine Grove Park | Port Huron | |||||||
| Marine City Informational Designation / Marine City City Hall† | 300 Broadway Street | Marine City | |||||||
| James McColl House† | 205 South Main Street | Yale | |||||||
| George H. McIntyre House | 4207 South River Road | St. Clair | |||||||
| Newport Academy | 405 South Main Street | Marine City | |||||||
| North Channel Shooting Club | 1001 North Channel, on the St. Clair River | Clay Township | |||||||
| Port Huron High School | 323 Erie Street | Port Huron | |||||||
| Ruby Methodist Church | 6650 Abbottsford Road, near Brott Road | Ruby | |||||||
| Sacred Heart Cemetery | Church Road, just north of Dixie Highway | Ira Township | 2018 | ||||||
| St. Andrew's Church / St. Andrew's Parish Informational Designation | 1507 St. Clair River Drive | Algonac | |||||||
| Saint Clair Inn† | 500 North Riverside Avenue | St. Clair | |||||||
| Saint Clair River Informational Designation | Algonac State Park, two miles north of Algonac | Clay Township | |||||||
| St. Clair River Tunnel‡ | Between Johnstone & Beard, near 10th Street (portal site) | Port Huron | |||||||
| Saint Johannes Evangelische Kirche | 710 Pine Street, at Seventh Street | Port Huron | |||||||
| Saint Mary's Catholic Church and Rectory | 415 North Sixth Street, between Vine and Orchard streets | St. Clair | |||||||
| St. Mary's Cemetery | Church Road, just north of Dixie Highway Across from Sacred Heart Cemetery | Ira Township | 2017 | ||||||
| Stewart Farm / Memoir of Aura Stewart | 2007 Stewart Road | Harsens Island | 2004 | ||||||
| Trinity Evangelical Lutheran Church | 1517 Tenth Street | Port Huron | |||||||
| Wales Township Hall | 1372 Wales Center | Wales Township | |||||||
| Ward-Holland House† | 433 North Main Street | Marine City | |||||||
| Water Speed Capital Commemorative Designation | Algonac City Park 1309 St. Clair River Drive | Algonac | |||||||
| E. C. Williams House | 2511 Tenth Avenue, between Hancock and Church streets | Port Huron | |||||||
| C. H. Wills & Company | Chrysler Plant, 840 Huron Avenue | Marysville | |||||||
| Woman's Benefit Association Building | 1338 Military Street | Port Huron |