The following is a list of Michigan State Historic Sites in Presque Isle County, Michigan. Sites marked with a dagger (†) are also listed on the National Register of Historic Places in Presque Isle County, Michigan.__TOC__
| width="30%" | Name | width="100px" | Image | Location | width="125px" | City | width="25px" | Listing date | |
|---|---|---|---|---|---|---|---|---|---|
| Burnham's Landing Informational Designation | Burnham's Landing Park, Grand Lake Rd at the foot of Pine View Street | Presque Isle | |||||||
| Elowsky Mill | Leer Road at intersection of Long Lake Road | Posen | |||||||
| Forty Mile Point Lighthouse† / Lake Huron Graveyard of Ships | Presque Isle County Park along US-23, 7 miles north of Rogers City | Rogers Township | |||||||
| John C. Kauffman House | 7993 East Grand Lake Road | Presque Isle | |||||||
| Lake Huron Informational Designation | Roadside Park on US-23, Huron Beach, near Hammond Bay Refuge Harbor, 26 miles north of Rogers City | Rogers Township | |||||||
| Metz Fire Informational Designation | Metz Township Hall, Gramba Road | Metz | |||||||
| Michigan Limestone and Chemical Company Quarry | 1035 Calcite Road | Rogers City | |||||||
| Old Presque Isle Lighthouse† | 5295 Grand Lake Road (Presque Isle Harbor) | Presque Isle Township | |||||||
| Presque Isle County Courthouse† | 20774 State Street | Onaway | |||||||
| Presque Isle Electric Cooperative Monument | Between 10957 and 10981 Michigan Street | Posen | |||||||
| Presque Isle Front Range Light | 5779 East Grand Lake Rd | Presque Isle Township | |||||||
| Presque Isle Light Station† | 4500 Grand Lake Road, N end of Presque Isle Harbor Peninsula | Presque Isle Township | |||||||
| Presque Isle Lodge† | 8211 East Grand Lake Road | Presque Isle Township |