The following is a list of Michigan State Historic Sites in Manistee County, Michigan. Sites marked with a dagger (†) are also listed on the National Register of Historic Places in Manistee County, Michigan.__TOC__
| width="30%" | Name | width="100px" | Image | Location | width="125px" | City | width="125px" | Listing date | |
|---|---|---|---|---|---|---|---|---|---|
| Simeon Babcock House† | 420 Third Street | Manistee | |||||||
| Camp Tosebo Historic District | 7228 Miller Road, Red Park | Manistee | |||||||
| Church of the Holy Trinity (Episcopal) and Rectory | 410 Second Street | Manistee | |||||||
| Danish Lutheran Church† | 300 Walnut Street | Manistee | |||||||
| William Douglas House | 521 Pine Street | Manistee | |||||||
| First Congregational Church† | 412 Fourth Street, between Oak and Maple streets | Manistee | |||||||
| First Scandinavian Lutheran Church | 331 Fourth Street | Manistee | |||||||
| Great Fire of 1871 Informational Designation | Orchard Beach State Park, 2 miles N of Manistee on M-110 | Manistee vicinity | |||||||
| Roscoe E. Harris Summer Cottage | 2254 Lakeisle Avenue, Portage Park Resort | Onekama | |||||||
| Hotel Wellston (Demolished) | 17201 6th Street | Wellston | |||||||
| House at Eastlake (Demolished) | Corner of Main and Goff streets | Eastlake | |||||||
| Kaleva Informational Designation | Wuoski Avenue | Kaleva | |||||||
| John J. Makinen Bottle House† | 14551 Wuoksi Avenue | Kaleva | |||||||
| Manistee City Library | 95 Maple Street | Manistee | |||||||
| Manistee County Courthouse Fountain† | Onekama Village Park | Onekama | |||||||
| Manistee Fire Hall | 281 First Street, SW corner of Hancock | Manistee | |||||||
| Harriet Quimby Childhood Home | 14789 Erdman Road | Arcadia | |||||||
| Ramsdell Theatre† | 101 Maple Street | Manistee | |||||||
| Sandenburgh-Rogers Summer Resort Complex† | 2046 Crescent Beach Road | Manistee | |||||||
| William W. Vincent House | 431 Cedar Street | Manistee |