The following is a list of Michigan State Historic Sites in Gratiot County, Michigan. Sites marked with a dagger (†) are also listed on the National Register of Historic Places in Gratiot County, Michigan.__TOC__
| width="30%" | Name | width="100px" | Image | Location | width="125px" | City | width="125px" | Listing date | |
|---|---|---|---|---|---|---|---|---|---|
| Alma College Informational Designation | 700 block West Superior Street | Alma | |||||||
| Alma Downtown Historic District | Superior Street | Alma | |||||||
| Alma Sugar Company Office Building and Seed House | 200 North Court (Office Building) and 217 North Court (Seed House) | Alma | |||||||
| Bethany Mission Cemetery | Riverside Drive north of McGregory Road | Bethany Township | |||||||
| Drake House | 328 East Saginaw Street | Breckenridge | 2009 | ||||||
| Gratiot Center Historical Village Barn | South Pine River Street | Ithaca | |||||||
| Gratiot County Courthouse† | Center Street, Courthouse Square | Ithaca | |||||||
| Jackson-Weller House | 129 W Center Street | Ithaca | |||||||
| John Jeffery House | 225 West Center Street | Ithaca | |||||||
| Stiles Kennedy House | 310 West Washington Street | St. Louis | |||||||
| James H. and Sarah W. Lancashire House | 633 North State Street | Alma | |||||||
| Lumberjack & Riverdrivers Association Park | Lumberjack Road, about 1.5 miles N of M-46 | Seville | |||||||
| Dr. Charles H. MacLachlan Sanitarium and House† | 6482 Pingree Road | Elwell | |||||||
| Michigan Masonic Home | 1200 Wright Avenue | Alma | |||||||
| Michigan's Petroleum Industry Informational Designation | Roadside rest area southbound US-27, north of Alma | Alma | |||||||
| NE Corner of West Center and North Maple | Ithaca | ||||||||
| Kosciusko P. Peet House | 228 West Center Street | Ithaca | |||||||
| Saginaw and Gratiot County State Road/Saginaw Valley and Saint Louis Railroad Commemorative Designation | Breckenridge Village Park, opposite 124 E Saginaw Street | Breckenridge | |||||||
| Second Presbyterian Church of Lafayette | 8026 East Street / Charles Road | Lafayette Township | |||||||
| Sumner Grist and Flour Mill (Demolished) | Mill Street | Sumner | |||||||
| Alfred Wasson Round Barn (Destroyed in a storm in 1998) | 1982 S Begole Road | Ithaca vicinity | |||||||
| A.W. Wright House | 503 North State Street | Alma |