The following is a list of Michigan State Historic Sites in Clinton County, Michigan. Sites marked with a dagger (†) are also listed on the National Register of Historic Places in Clinton County, Michigan.__TOC__
| width="30%" | Name | width="100px" | Image | Location | width="125px" | City | width="125px" | Listing date | |
|---|---|---|---|---|---|---|---|---|---|
| Banner Grange No. 1240 Hall | Banner Road west of DeWitt Road | Greenbush Township | |||||||
| Bath Community Hall | 13639 Main Street | Bath | |||||||
| Bath School Disaster Informational Site | Main Street between High Street and Clark Road | Bath | |||||||
| John H. Clements Homestead (Demolished) | 2480 East Clark Road | DeWitt Township | |||||||
| Coleman's Hotel | Southeast corner of US-127 and French Road | Greenbush Township | |||||||
| DeWitt Old Methodist Episcopal Church | 115 North Bridge Street | DeWitt | |||||||
| Roswell C. Dexter House | 200 South Church Street | St. Johns | |||||||
| East Ward School-demolished† | 106 North Traver Street | St. Johns | |||||||
| First Congregational Church of Ovid† | 222 Main Street | Ovid | |||||||
| Greenbush United Methodist Church | Northwest corner of Scott Road and Marshall Road | Greenbush Township | |||||||
| Gunnisonville Historic District | Southeast and northeast corners of East Clark Road and Wood Road | DeWitt Township | |||||||
| Indian History in Central Michigan | DeWitt Township | ||||||||
| Maple Rapids Methodist Episcopal Church | 330 South Maple Avenue | Maple Rapids | |||||||
| Matthews Site | 7000-7502 N Lowell Rd (end of Lowell Road, 2 miles east of Maple Rapids) | Essex Township | |||||||
| Michigan's Capital Commemorative Designation | Roadside Park, I-96, west of Lansing | Watertown Township | |||||||
| John W. Paine House | 106 Maple Street | St. Johns | |||||||
| Philip Parmelee Clinton County Informational Designation | Capital Region International Airport | DeWitt Township | |||||||
| Henry M. Perrin-Dr. Henry Palmer House | 903 North Clinton Avenue | St. Johns | |||||||
| Rochester Colony | Friendship Park, Maple Road | DuPlain Township | |||||||
| Saint Mary's Church / Westphalia Settlement Informational Designation | 201 North Westphalia Street | Westphalia | |||||||
| Saint Peter Evangelical Lutheran Church | 8990 Church Road | St. Johns | |||||||
| Joshua Simmons II Burial Place | North Eagle Cemetery, Grange Road, south of Howe Road | Eagle Township | |||||||
| G. D. Sowers House | 131 East Williams Street | Ovid | |||||||
| St. John's Church | North Mead Street and East Walker Street | St. Johns | |||||||
| St. Johns Union School† | 205 West Baldwin Street | St. Johns | |||||||
| Steel Hotel (Demolished) | US-27 and M-21 | St. Johns |