This is a list of the Canadian Billboard magazine Canadian Hot 100 number-ones of 2010.
Note that Billboard publishes charts with an issue date approximately 7–10 days in advance.
| Indicates best-performing single of 2010[1] |
| Issue date | Song | Artist(s) | Reference | ||
|---|---|---|---|---|---|
| 31 | January 2 | "Tik Tok" | [2] | ||
| January 9 | |||||
| January 16 | |||||
| January 23 | |||||
| January 30 | |||||
| February 6 | |||||
| February 13 | |||||
| 32 | February 20 | "Today Was a Fairytale" | [3] | ||
| 33 | February 27 | "I Believe" | [4] | ||
| March 6 | |||||
| March 13 | |||||
| March 20 | |||||
| 34 | March 27 | "Wavin' Flag" | [5] | ||
| April 3 | |||||
| April 10 | |||||
| April 17 | |||||
| April 24 | |||||
| May 1 | |||||
| 35 | May 8 | "Break Your Heart" | Taio Cruz featuring Ludacris | [6] | |
| May 15 | |||||
| 36 | May 22 | "Not Afraid" | [7] | ||
| 37 | May 29 | bgcolor=#FFFF99 align="center" rowspan="9" | "California Gurls" | [8] | |
| June 5 | |||||
| June 12 | |||||
| June 19 | |||||
| June 26 | |||||
| July 3 | |||||
| July 10 | |||||
| July 17 | |||||
| July 24 | |||||
| 38 | July 31 | "Love the Way You Lie" | [9] | ||
| August 7 | |||||
| August 14 | |||||
| August 21 | |||||
| August 28 | |||||
| September 4 | |||||
| September 11 | |||||
| 39 | September 18 | "Dynamite" | Taio Cruz | [10] | |
| 40 | September 25 | "I Like It" | Enrique Iglesias featuring Pitbull | [11] | |
| 41 | October 2 | "Only Girl (In the World)" | Rihanna | [12] | |
| 42 | October 9 | "Just the Way You Are" | [13] | ||
| October 16 | |||||
| October 23 | |||||
| October 30 | |||||
| re | November 6 | "Only Girl (In the World)" | Rihanna | [14] | |
| November 13 | |||||
| November 20 | |||||
| 43 | November 27 | "" | [15] | ||
| December 4 | |||||
| December 11 | |||||
| 44 | December 18 | "Firework" | Katy Perry | [16] | |
| re | December 25 | "The Time (Dirty Bit)" | The Black Eyed Peas | [17] | |