| Post: | High Commissioner of the United Kingdom to Ghana |
| Seat: | Ghana |
| Inaugural: | Sir Ian Maclennan |
| Formation: | 1957 |
| Appointer: | Secretary of State for Foreign and Commonwealth Affairs |
| Style: | Her Excellency |
| Nominator: | Prime Minister of the United Kingdom |
| Residence: | Osu Link, Gamel Abdul Nasser Avenue |
| Incumbentsince: | 2021 |
| Incumbent: | Harriet Thompson |
| Insigniacaption: | Coat of Arms of the United Kingdom |
| Insigniasize: | 120px |
| Insignia: | Royal Coat of Arms of the United Kingdom (HM Government) (2022).svg |
| Website: | British High Commission – Ghana |
The high commissioner of the United Kingdom to Ghana is the United Kingdom's foremost diplomatic representative in the Republic of Ghana, and head of the UK's diplomatic mission in Ghana.
As fellow members of the Commonwealth of Nations, the United Kingdom and Ghana conduct their diplomatic relations at governmental level, rather than between heads of state. Therefore, the countries exchange high commissioners, rather than ambassadors.