This is a list of Fantastic Beasts cast members who portrayed or voiced characters appearing in the film series. The list below is sorted by film and the character's surname, as some characters have been portrayed by multiple actors.
| Character | 2016 | 2018 | 2022 |
|---|---|---|---|
| Fantastic Beasts | The Crimes of Grindelwald | The Secrets of Dumbledore | |
Introduced in the Harry Potter film series | |||
| Aberforth Dumbledore | Richard Coyle | ||
| Albus Dumbledore | Jude Law Toby Regbo | Jude Law | |
| Gellert Grindelwald | Colin Farrell Johnny Depp | Johnny Depp Jamie Campbell Bower | Mads Mikkelsen |
| Minerva McGonagall | Fiona Glascott | ||
| Nagini | Claudia Kim | ||
Introduced in Fantastic Beasts and Where to Find Them | |||
| Abernathy | Kevin Guthrie | ||
| Credence Barebone | Ezra Miller | ||
| Chastity Barebone | Jenn Murray | colspan="2" | |
| Mary Lou Barebone | Samantha Morton | colspan="2" | |
| Modesty Barebone | Faith Wood-Blagrove | colspan="2" | |
| Gnarlak | Ron Perlman | colspan="2" | |
| Porpentina Esther "Tina" Goldstein | Katherine Waterston | Katherine Waterston | |
| Queenie Goldstein | Alison Sudol | ||
| Jacob Kowalski | Dan Fogler | ||
| Seraphina Picquery | Carmen Ejogo | ||
| Newt Scamander | Eddie Redmayne | Eddie Redmayne Joshua Shea | Eddie Redmayne |
| Henry Shaw Jr | Josh Cowdery | colspan="2" | |
| Henry Shaw Sr | Jon Voight | colspan="2" | |
| Langdon Shaw | Ronan Raftery | colspan="2" | |
| Madam Ya Zhou | Gemma Chan | colspan="2" | |
| Leta Lestrange | Zoë Kravitz Thea Lamb Ruby Woolfenden | ||
Introduced in The Crimes of Grindelwald | |||
| Bunty Broadacre | Victoria Yeates | ||
| Carrow | Maja Bloom | ||
| Irma Dugard | Danielle Hugues | ||
| Nicolas Flamel | Brontis Jodorowsky | ||
| Grimmson | Ingvar Eggert Sigurðsson | ||
| Eulalie "Lally" Hicks | Jessica Williams | ||
| Laurena Kama | Isaura Barbé-Brown | ||
| Yusuf Kama | William Nadylam Isaac Domingos | William Nadylam | |
| Krall | David Sakurai | ||
| Vinda Rosier | Poppy Corby-Tuech | ||
| Theseus Scamander | Callum Turner | ||
| Skender | Ólafur Darri Ólafsson | ||
Introduced in The Secrets of Dumbledore | |||
| Edith | Ramona Kunze-Libnow | ||
| Henrietta Fischer | Valerie Pachner | ||
| Helmut | Aleksandr Kuznetsov | ||
| Otto | Matthias Brenner | ||
| Vicência Santos | Maria Fernanda Cândido | ||
| Liu Tao | Dave Wong | ||
| Anton Vogel | Oliver Masucci | ||
| Warder | Peter Simonischek | ||