The following is a list of defectors from the Commonwealth of Independent States. The Commonwealth is an intergovernmental organization formed after the dissolution of the Soviet Union as its legal successor. This list of defectors is not to be confused with Soviet defectors.
| Kanatjan Alibekov | Bioweapons chief | Kazakhstan | 1992 | Former director of Biopreparat; defected to the United States | |
| GRU agent | Russia | 1992 | Defected to the U.S.; revealed the existence of KGB weapons caches in the West | ||
| KGB agent | Russia | 1992 | KGB archivist who was shocked by records of Soviet political repression; defected in Riga, Latvia to the British embassy | ||
| Sergei Tretyakov | SVR agent | Russia | 2000 | Defected in New York City to the CIA; Deputy Resident Station Chief in New York City; revealed many political and intelligence secrets from Russia; sudden death occurred in Sarasota County, Florida, on June 13, 2010; foul play has been alleged | |
| FSB agent | Russia | 2000 | Exposed crimes ordered by Russian president Vladimir Putin; defected in London, United Kingdom; assassinated | ||
| Denis Sharonov | Russia | 2022 | Defected to the U.S. via Kyrgyzstan, the United Arab Emirates, and Mexico to avoid conscription in the Russian Army following the invasion of Ukraine, which he blamed on his falling out with officials of the regional government[1] | ||
| Maksim Kuzminov | Pilot | Russia | 2023 | Attack pilot of the 319th Separate Helicopter Regiment of the Eastern Military District;[2] defected to Ukraine in a Mi-8AMTSh helicopter during the Russian invasion[3] |