These are the singles that reached number one on the Top 100 Singles chart in 1987 as published by Cash Box magazine.
| Indicates best-performing single of 1987 |
| Issue date | Song | Artist | |
|---|---|---|---|
| January 3 | "Everybody Have Fun Tonight" | Wang Chung | |
| January 10 | |||
| January 17 | "Shake You Down" | Gregory Abbott | |
| January 24 | |||
| January 31 | "At This Moment" | Billy Vera & the Beaters | |
| February 7 | "Open Your Heart" | Madonna | |
| February 14 | "Livin' on a Prayer" | ||
| February 21 | |||
| February 28 | |||
| March 7 | |||
| March 14 | "Jacob's Ladder" | ||
| March 21 | "Lean On Me" | ||
| March 28 | |||
| April 4 | "Nothing's Gonna Stop Us Now" | ||
| April 11 | |||
| April 18 | |||
| April 25 | "I Knew You Were Waiting (For Me)" | ||
| May 2 | "(I Just) Died in Your Arms" | ||
| May 9 | |||
| May 16 | "With or Without You" | ||
| May 23 | |||
| May 30 | |||
| June 6 | "Always" | ||
| June 13 | |||
| June 20 | bgcolor=#FFFF99 rowspan="2" | "Head to Toe" | |
| June 27 | |||
| July 4 | "I Wanna Dance with Somebody (Who Loves Me)" | ||
| July 11 | |||
| July 18 | "Alone" | ||
| July 25 | |||
| August 1 | "Shakedown" | ||
| August 8 | "I Still Haven't Found What I'm Looking For" | ||
| August 15 | |||
| August 22 | "Who's That Girl" | Madonna | |
| August 29 | "La Bamba" | ||
| September 5 | |||
| September 12 | "I Just Can't Stop Loving You" | ||
| September 19 | |||
| September 26 | "Didn't We Almost Have It All" | ||
| October 3 | "Here I Go Again" | ||
| October 10 | |||
| October 17 | "Lost in Emotion" | ||
| October 24 | "Bad" | ||
| October 31 | |||
| November 7 | "I Think We're Alone Now" | Tiffany | |
| November 14 | |||
| November 21 | "Mony Mony (Live)" | Billy Idol | |
| November 28 | "(I've Had) The Time of My Life" | ||
| December 5 | "Heaven Is a Place on Earth" | Belinda Carlisle | |
| December 12 | "Faith" | George Michael | |
| December 19 | |||
| December 26 |