This is a list of singles that charted in the top ten of the Billboard Global 200, an all-genre singles chart, in 2021.
Key
See main article: List of Billboard Global 200 top 10 singles of 2020.
| Weeks in top ten | |||||||
| "Dynamite" (#5) | BTS | 1 | 26 | ||||
| "Mood" (#10) | 24kGoldn featuring Iann Dior | 2 | 25 | ||||
| "Positions" | Ariana Grande | 1 | 10 | ||||
| "Dakiti" (#6) | Bad Bunny and Jhay Cortez | 1 | 18 |
See main article: List of Billboard Global 200 top 10 singles of 2022.
| Weeks in top ten | |||||||
| "Heat Waves" | Glass Animals | 1 | 32 | ||||
| "Cold Heart (Pnau Remix)" | Elton John and Dua Lipa | 3 | 29 | ||||
| "abcdefu" | Gayle | 1 | 22 |
| Weeks in top ten | ||||||
| "All I Want for Christmas Is You" | Mariah Carey | 1 | 16 | |||
| "Last Christmas" | Wham! | 2 | 15 | |||
| "Rockin' Around the Christmas Tree" | Brenda Lee | 2 | 14 | |||
| "Jingle Bell Rock" | Bobby Helms | 4 | 14 | |||
| "It's Beginning to Look a Lot Like Christmas" | Michael Buble | 6 | 7 | |||
| "Santa Tell Me" | Ariana Grande | 5 | 9 | |||
| "It's the Most Wonderful Time of the Year" | Andy Williams | 7 | 6 | |||
| "Underneath the Tree" | Kelly Clarkson | 8 | 2 | |||
| "Feliz Navidad" | Jose Feliciano | 5 | 4 |
A remix of Ariana Grande's "34+35" that features Doja Cat and Megan Thee Stallion helped to bring the song back into the top ten, to its peak position of number 2, on January 30, 2021, and all three artists were credited on the song that week. As of the February 6, 2021 chart, Grande returned to being the only artist credited.
Ariana Grande is credited on a remix of The Weeknd's "Save Your Tears", with her name appearing on the song beginning with the Global 200 chart dated May 8, 2021. Prior to that week, The Weeknd was the sole artist credit.
In August 2021, with Dua Lipa's "Levitating" having already been in the top ten for more than 30 weeks, DaBaby was no longer listed as a featured artist on the song.[2] His name is being retained on the entry as he was credited for a majority of the song's run in the top ten, including the week it peaked at number two.
A remix of The Kid Laroi's "Without You" that features Miley Cyrus helped to bring the song into the top 10 at its peak position of number 10 on May 15, 2021, and Miley Cyrus was credited on the song that week.
A remix of BTS's "Butter" that features Megan Thee Stallion helped to bring the song back into the top 10 at number 3 on September 11, 2021, and Megan Thee Stallion was credited on the song that week.
The Weeknd's "Take My Breath" re-entered the top ten on January 22, 2022 upon the release of its parent album Dawn FM. The Dawn FM album version of "Take My Breath" is an extended version of the song.
The single re-entered the top ten on the week ending January 2, 2021.
The single re-entered the top ten on the week ending January 9, 2021.
The single re-entered the top ten on the week ending January 16, 2021.
The single re-entered the top ten on the week ending January 30, 2021.
The single re-entered the top ten on the week ending February 6, 2021.
The single re-entered the top ten on the week ending March 6, 2021.
The single re-entered the top ten on the week ending March 27, 2021.
The single re-entered the top ten on the week ending April 3, 2021.
The single re-entered the top ten on the week ending June 5, 2021.
The single re-entered the top ten on the week ending July 17, 2021.
The single re-entered the top ten on the week ending September 11, 2021.
The single re-entered the top ten on the week ending September 25, 2021.
The single re-entered the top ten on the week ending October 2, 2021.
The single re-entered the top ten on the week ending October 9, 2021.
The single re-entered the top ten on the week ending November 13, 2021.
The single re-entered the top ten on the week ending December 11, 2021.
The single re-entered the top ten on the week ending December 18, 2021.
The single re-entered the top ten on the week ending December 25, 2021.