This is a list of Akhisarspor's managers and their respective honours, from 2000, when the first professional manager was appointed, to the present day.[1]
| Name | From | To | Honours | ||
|---|---|---|---|---|---|
| Adnan Özbağcı | 7 June 2000 | 6 October 2000 | |||
| Can Cangök | 12 October 2000 | 30 June 2003 | |||
| Turgut Uçar | 7 August 2003 | 30 June 2004 | |||
| Atilla Özcan | 13 April 2005 | 20 February 2006 | |||
| Mustafa Serin | 29 August 2006 | 16 October 2006 | |||
| Atilla Özcan | 18 October 2006 | 1 March 2011 | |||
| Hamza Hamzaoğlu | 3 March 2011 | 30 June 2014 | TFF First League (1) | ||
| Mustafa Reşit Akçay | 1 July 2014 | 29 December 2014 | |||
| Roberto Carlos | 3 January 2015 | 1 June 2015 | |||
| Cihat Arslan | 1 July 2015 | 1 September 2016 | |||
| 6 September 2016 | 18 March 2017 | ||||
| 23 March 2017 | 30 June 2018 | Turkish Cup (1) | |||
| Safet Sušić | 30 June 2018 | 17 September 2018 | Turkish Super Cup (1) | ||
| Cihat Arslan | 25 September 2018 | 13 February 2019 | |||
| Cem Kavçak | 13 February 2019 | 30 June 2019 | |||
| Mehmet Altıparmak | 26 June 2019 | 27 January 2020 | |||
| Yılmaz Vural | 28 January 2020 | 31 July 2020 | |||
| Cem Kavçak | 8 August 2020 | 31 August 2020 | |||
| Ercan Kahyaoğlu | 1 September 2020 | 9 December 2020 | |||
| Mesut Dilsöz | 10 December 2020 | 25 February 2021 | |||
| Firat Gül | 26 February 2021 | 15 March 2021 | |||
| Mustafa Göksu | 16 March 2021 | present |