This is a list of films which ranked number one at the weekend box office for the year 2022 in India.
| 1 | 9 January 2022 | $1,020,000 | English | |
| 2 | 16 January 2022 | Bangarraju | $1,122,411 | Telugu |
| 3 | 23 January 2022 | The King's Man | $19,278 | English |
| 4 | 30 January 2022 | Scream | $85,235 | |
| 5 | 6 February 2022 | Veeramae Vaagai Soodum | $1,056,978 | Tamil |
| 6 | 13 February 2022 | Badhaai Do | $3,336,745 | Hindi |
| 7 | 20 February 2022 | Aaraattu | $3,282,023 | Malayalam |
| 8 | 27 February 2022 | Bheemla Nayak | $18,787,720 | Telugu |
| 9 | 6 March 2022 | The Batman | $6,871,377 | English |
| 10 | 13 March 2022 | Radhe Shyam | $18,216,290 | TeluguHindi |
| 11 | 20 March 2022 | The Kashmir Files | $14,169,020 | Hindi |
| 12 | 27 March 2022 | RRR | $42,674,401 | Telugu |
| 13 | 3 April 2022 | $18,538,384 | ||
| 15 | 17 April 2022 | $40,021,684 | Kannada | |
| 16 | 24 April 2022 | $15,680,985 | ||
| 17 | 1 May 2022 | Acharya | $5,804,799 | Telugu |
| 18 | 8 May 2022 | Doctor Strange in the Multiverse of Madness | $12,676,832 | English |
| 19 | 15 May 2022 | Sarkaru Vaari Paata | $11,336,013 | Telugu |
| 20 | 22 May 2022 | Bhool Bhulaiyaa 2 | $11,028,752 | Hindi |
| 21 | 29 May 2022 | $6,146,535 | ||
| 22 | 5 June 2022 | Vikram | $20,920,610 | Tamil |
| 23 | 12 June 2022 | Jurassic World Dominion | $15,353,634 | English |
| 24 | 19 June 2022 | 777 Charlie | $5,072,479 | Kannada |
| 25 | 26 June 2022 | Jugjugg Jeeyo | $4,425,891 | Hindi |
| 26 | 3 July 2022 | $2,666,966 | ||
| 27 | 10 July 2022 | $10,800,413 | English | |
| 28 | 17 July 2022 | The Warriorr | $6,554,578 | Telugu |
| 29 | 24 July 2022 | Malayankunju | $2,390,498 | Malayalam |
| 30 | 31 July 2022 | Ek Villain Returns | $4,059,789 | Hindi |
| 31 | 7 August 2022 | Bimbisara | $4,857,056 | Telugu |
| 32 | 14 August 2022 | Laal Singh Chaddha | $11,878,910 | Hindi |
| 33 | 21 August 2022 | Thiruchitrambalam | $5,691,528 | Tamil |
| 34 | 28 August 2022 | Liger | $4,499,645 | TeluguHindi |
| 35 | 4 September 2022 | Cobra | $4,610,141 | Tamil |
| 36 | 11 September 2022 | $17,866,222 | Hindi | |
| 37 | 18 September 2022 | $6,291,081 | ||
| 38 | 25 September 2022 | $5,747,453 | ||
| 39 | 2 October 2022 | $20,457,950 | Tamil | |
| 40 | 9 October 2022 | Godfather | $21,331,008 | Telugu |
| 41 | 16 October 2022 | Doctor G | $1,924,376 | Hindi |
| 42 | 23 October 2022 | Black Adam | $7,882,119 | English |
| 43 | 30 October 2022 | Gandhada Gudi | $2,182,521 | Kannada |
| 44 | 6 November 2022 | Mrs. Harris Goes to Paris | $23,530 | English |
| 45 | 13 November 2022 | $6,432,078 | ||
| 46 | 20 November 2022 | $2,018,003 | ||
| 47 | 27 November 2022 | $395,939 | ||
| 48 | 4 December 2022 | $212,563 | ||
| 49 | 11 December 2022 | $93,259 | ||
| 50 | 18 December 2022 | $19,158,636 | ||
| 51 | 25 December 2022 | $8,946,538 | ||
| 52 | 1 January 2023 | $6,078,573 |
| 1 | Kannada | [3] | ||
| 2 | RRR | crore | Telugu | [4] |
| 3 | crore | English | [5] | |
| 4 | Kantara | Kannada | [6] | |
| 5 | 326.50 crore | Tamil | [7] | |
| 6 | crore | Hindi | ||
| 7 | Vikram | 302.5crore | Tamil | [8] |
| 8 | The Kashmir Files | Hindi | [9] | |
| 9 | Drishyam 2 | crore | ||
| 10 | Bhool Bhulaiyaa 2 | crore | [10] | |
| U | F3 (film) | F3 |
| U/A | ||
| A | The Kashmir Files |