| Date | Film | Gross (USD) | Openings in the top ten |
|---|
| 1 | | | $2,483,602 | Concussion (#3), Solace (#5), El Cumple de la Abuela (#8) |
| 2 | | Point Break | $1,923,839 | Joy (#5), Summer Camp (#7), The Big Short (#8) |
| 3 | | $1,193,286 | The Danish Girl (#2), (#4), Pay the Ghost (#7) |
| 4 | | The Revenant | $4,485,305 | |
| 5 | | Daddy's Home | $2,421,009 | The 5th Wave (#3), The Boy (#4), Creed (#5) |
| 6 | | $1,297,703 | Norm of the North (#5), Fifty Shades of Black (#8), The Hateful Eight (#9), Pride and Prejudice and Zombies (#10) |
| 7 | | Deadpool | $7,226,374 | Busco Novio Para mi Mujer (#2), Visions (#9), Carol (#10) |
| 8 | | Zootopia | $4,564,709 | How to Be Single (#3), The Forest (#5), Room (#6) |
| 9 | | $3,291,823 | Gods of Egypt (#3), Zoolander 2 (#4), (#5), The Finest Hours (#6) |
| 10 | | $2,403,856 | Dirty Grandpa (#4), Backtrack (#6), (#8), The Choice (#9) |
| 11 | | Kung Fu Panda 3 | $5,172,092 | London Has Fallen (#3), Paraíso Perdido (#7), The Young Messiah (#9) |
| 12 | | $3,002,381 | (#2), Risen (#6), Irrational Man (#10) |
| 13 | | | $12,256,287 | My Big Fat Greek Wedding 2 (#5), Capture the Flag (#6), Truth (#10) |
| 14 | | $5,386,095 | Compadres (#2), Miracles from Heaven (#3), Eddie the Eagle (#5) |
| 15 | | | $2,777,671 | The Jungle Book 3D (#3), Burnt (#7), Chronic (#9) |
| 16 | | The Jungle Book | $6,588,342 | 10 Cloverfield Lane (#4), Desierto (#5), (#8) |
| 17 | | $5,282,187 | Eye in the Sky (#3), Before I Wake (#5), Sundown (#9), God's Not Dead 2 (#10) |
| 18 | | | $20,472,106 | Youth (#9) |
| 19 | | $6,770,483 | Mother's Day (#3), The Other Side of the Door (#4), My King (#10) |
| 20 | | ¿Qué Culpa Tiene el Niño? | $3,582,114 | The Angry Birds Movie (#2) |
| 21 | | | $6,982,357 | The Witch (#4), Rumbos Paralelos (#6), Labyrinth of Lies (#8) |
| 22 | | Alice Through the Looking Glass | $4,545,297 | (#4), Fathers and Daughters (#7) |
| 23 | | | $3,721,182 | Tini: El Gran Cambio de Violetta (#8) |
| 24 | | The Conjuring 2 | $7,458,608 | A Hologram for the King (#6), De Surprise (#9), Ratchet & Clank (#10) |
| 25 | | $3,447,284 | Warcraft (#2), Money Monster (#5), Pinocchio (#8) |
| 26 | | | $6,807,844 | Me Before You (#2) |
| 27 | | | $8,453,629 | Central Intelligence (#4), La Niña De La Mina (#6), Louder Than Bombs (#9) |
| 28 | | The Legend of Tarzan | $4,519,253 | The Nice Guys (#6), The Faith of Anna Waters (#7), Julieta (#9) |
| 29 | | Finding Dory | $9,537,312 | The Shallows (#4) |
| 30 | | $4,090,870 | Now You See Me 2 (#2), Criminal (#5), Cell (#9) |
| 31 | | The Secret Life of Pets | $7,496,779 | Lights Out (#2), The Wave (#6), Batman: The Killing Joke (#10) |
| 32 | | Suicide Squad | $10,346,298 | The Whole Truth (#6), East Side Sushi (#10) |
| 33 | | $4,371,410 | Ghostbusters (#2), The BFG (#4), Free State of Jones (#9) |
| 34 | | Ben-Hur | $2,683,725 | (#3), Me Estás Matando Susana (#7), Skiptrace (#9) |
| 35 | | Jason Bourne | $1,507,072 | Bad Moms (#5) |
| 36 | | Mike and Dave Need Wedding Dates | $1,023,116 | Nine Lives (#6), Nerve (#7) |
| 37 | | Star Trek Beyond | $1,286,108 | (#2) |
| 38 | | No Manches Frida | $3,226,095 | Pete's Dragon (#2), Don't Breathe (#3), Bridget Jones's Baby (#4) |
| 39 | | Storks | $2,425,893 | Bastille Day (#5), The Magnificent Seven (#7), The Light Between Oceans (#9), (#10) |
| 40 | | Miss Peregrine's Home for Peculiar Children | $3,603,032 | Deepwater Horizon (#4), Blair Witch (#5) |
| 41 | | Treintona, Soltera y Fantástica | $2,364,087 | Kubo and the Two Strings (#5), Blood Father (#8), Sausage Party (#9), Viral (#10) |
| 42 | | Inferno | $2,545,428 | Masterminds (#5) |
| 43 | | | $2,211,371 | La Leyenda del Chupacabras (#2), La Vida Inmoral de la Pareja Ideal (#6), The Infiltrator (#8) |
| 44 | | Doctor Strange | $4,608,705 | El Jeremías (#4) |
| 45 | | Trolls | $2,645,678 | The Accountant (#3), KM 31-2 (#4), Until Forever (#10) |
| 46 | | $1,661,909 | The Girl on the Train (#3), Arrival (#5), Macho (#6), Robinson Crusoe (#8) |
| 47 | | Fantastic Beasts and Where to Find Them | $5,774,215 | The 9th Life of Louis Drax (#8), Café Society (#9) |
| 48 | | $2,602,427 | (#2), Shut In (#4), Keeping Up with the Joneses (#5) |
| 49 | | Moana | $2,880,517 | (#2), Sully (#3), Qué Pena Tu Vida (#5) |
| 50 | | $2,359,271 | Office Christmas Party (#2), Train to Busan (#6), Blackway (#10) |
| 51 | | Rogue One: A Star Wars Story | $5,129,571 | Collateral Beauty (#2), The Disappointments Room (#5) |
| 52 | | Sing | $1,701,157 | Passengers (#3), Un Padre No Tan Padre (#4), Why Him? (#7) |
| 53 | | $1,552,491 | Ballerina (#4), Hacksaw Ridge (#6), Assassin's Creed (#8) | |
