This is a list of films which have placed number one at the weekend box office in Venezuela during 2012.
| Date | Film | Gross | Notes | |
|---|---|---|---|---|
| 1 | Puss in Boots | $508,067 | ||
| 2 | Jack and Jill | $559,537 | ||
| 3 | Jack and Jill | $487,956 | ||
| 4 | Jack and Jill | $421,975 | ||
| 5 | $429,488 | |||
| 6 | $400,329 | |||
| 7 | Mission: Impossible – Ghost Protocol | $353,657 | ||
| 8 | $564,947 | |||
| 9 | Underworld: Awakening | $466,658 | ||
| 10 | John Carter | $564,797 | ||
| 11 | John Carter | $519,075 | ||
| 12 | John Carter | $326,075 | ||
| 13 | Wrath of the Titans | $1,016,412 | ||
| 14 | Wrath of the Titans | $1,083,909 | ||
| 15 | Wrath of the Titans | $708,944 | ||
| 16 | The Lorax | $509,058 | ||
| 17 | The Avengers | $1,585,295 | ||
| 18 | The Avengers | $1,458,620 | ||
| 19 | The Avengers | $1,037,153 | ||
| 20 | The Avengers | $1,060,276 | ||
| 21 | Men in Black 3 | $1,220,259 | ||
| 22 | Men in Black 3 | $1,027,778 | ||
| 23 | $1,298,255 | |||
| 24 | Madagascar 3: Europe's Most Wanted | $1,379,283 | ||
| 25 | Madagascar 3: Europe's Most Wanted | $1,175,481 | ||
| 26 | Madagascar 3: Europe's Most Wanted | $1,146,333 | ||
| 27 | The Amazing Spider-Man | $1,332,196 | ||
| 28 | The Amazing Spider-Man | $1,036,574 | ||
| 29 | $2,056,823 | Ice Age: Continental Drift had the highest weekend debut of 2012. | ||
| 30 | Ice Age: Continental Drift | $1,566,568 | ||
| 31 | Ice Age: Continental Drift | $1,319,390 | ||
| 32 | Brave | $1,204,704 | ||
| 33 | Brave | $1,162,196 | ||
| 34 | Brave | $882,282 | ||
| 35 | Brave | $668,178 | ||
| 36 | Prometheus | $525,152 | ||
| 37 | $1,027,114 | |||
| 38 | Resident Evil: Retribution | $701,790 | ||
| 39 | Resident Evil: Retribution | $474,645 | ||
| 40 | Resident Evil: Retribution | $219,455 | ||
| 41 | $497,457 | |||
| 42 | The Snitch Cartel | $482,488 | ||
| 43 | The Snitch Cartel | $487,457 | ||
| 44 | ParaNorman | $660,583 | ||
| 45 | ParaNorman | $526,420 | ||
| 46 | $2,043,910 | |||
| 47 | The Twilight Saga: Breaking Dawn – Part 2 | $1,419,153 | ||
| 48 | The Twilight Saga: Breaking Dawn – Part 2 | $821,204 | ||
| 49 | Hotel Transylvania | $667,108 | ||
| 50 | Hotel Transylvania | $547,382 | ||
| 51 | $625,458 | |||
| 52 | Wreck-It Ralph | $1,066,015 | ||
| Rank | Title | Studio | Domestic Gross | |
|---|---|---|---|---|
| 1. | 20th Century Fox / Blue Sky Studios | $14,680,514 | ||
| 2. | The Avengers | Walt Disney Pictures / Marvel Studios | $13,216,039 | |
| 3. | Paramount Pictures / DreamWorks Animation | $12,554,510 | ||
| 4. | Wreck-It Ralph | Walt Disney Pictures | $11,182,824 | |
| 5. | Brave | Walt Disney Pictures / Pixar Animation Studios | $10,180,176 | |
| 6. | Summit Entertainment | $9,353,315 | ||
| 7. | The Amazing Spider-Man | Columbia Pictures | $7,386,300 | |
| 8. | The Dark Knight Rises | Warner Bros. / DC Entertainment | $7,143,582 | |
| 9. | Wrath of the Titans | Warner Bros. | $6,820,191 | |
| 10. | Men in Black 3 | Columbia Pictures | $5,465,350 |