This is a list of films which have placed number one at the weekend box office in Poland during 2010.
| Date | Film | Gross | Notes | |
|---|---|---|---|---|
| 1 | Avatar | $2,941,552 | ||
| 2 | $2,271,580 | |||
| 3 | $1,943,351 | |||
| 4 | $1,632,087 | |||
| 5 | $1,440,446 | |||
| 6 | $1,231,132 | |||
| 7 | Randka w ciemno | $1,342,325 | Randka w ciemno reached No. 1 in its second weekend of release. | |
| 8 | Avatar | $938,836 | ||
| 9 | $792,168 | |||
| 10 | Alice in Wonderland | $2,006,542 | ||
| 11 | $1,508,310 | |||
| 12 | $905,050 | |||
| 13 | $507,952 | |||
| 14 | $120,908 | |||
| 15 | Clash of the Titans | $572,559 | ||
| 16 | How to Train Your Dragon | $258,460 | ||
| 17 | $708,640 | |||
| 18 | $639,451 | |||
| 19 | $335,097 | |||
| 20 | Robin Hood | $1,065,354 | ||
| 21 | Prince of Persia: The Sands of Time | $641,128 | ||
| 22 | Disco ormene | $535,978 | ||
| 23 | $275,572 | |||
| 24 | $135,498 | |||
| 25 | Toy Story 3 | $906,486 | ||
| 26 | $483,072 | |||
| 27 | $838,330 | |||
| 28 | Shrek Forever After | $2,625,401 | Shrek Forever After had the highest weekend debut of 2010. | |
| 29 | $2,274,107 | |||
| 30 | $1,796,513 | |||
| 31 | Inception | $975,339 | ||
| 32 | Step Up 3D | $1,001,622 | ||
| 33 | $525,679 | |||
| 34 | Despicable Me | $372,571 | ||
| 35 | Salt | $562,415 | ||
| 36 | The Last Airbender | $430,373 | ||
| 37 | $494,633 | |||
| 38 | Space Dogs 3D | $270,770 | ||
| 39 | StreetDance 3D | $350,403 | ||
| 40 | $482,542 | |||
| 41 | Maiden Vows | $1,065,220 | ||
| 42 | $934,494 | |||
| 43 | $526,259 | |||
| 44 | Saw 3D | $822,321 | ||
| 45 | $449,559 | |||
| 46 | Śniadanie do łóżka | $733,062 | ||
| 47 | Harry Potter and the Deathly Hallows – Part 1 | $2,499,386 | ||
| 48 | $1,069,927 | |||
| 49 | Tangled | $718,509 | Tangled reached No. 1 in its second weekend of release. | |
| 50 | $537,004 | |||
| 51 | $266,155 | |||
| 52 | $292,380 | |||
| 53 | $436,993 | |||