This is a list of films which have placed number one at the weekend box office in Chile during 2008.
| Date | Film | Gross | Notes | ||
|---|---|---|---|---|---|
| 1 | $123,862 | ||||
| 2 | Enchanted | $107,061 | |||
| 3 | I Am Legend | $312,762 | |||
| 4 | $154,075 | ||||
| 5 | $115,174 | ||||
| 6 | Cloverfield | $95,123 | |||
| 7 | $93,698 | ||||
| 8 | $70,187 | ||||
| 9 | American Gangster | $80,601 | |||
| 10 | 10,000 BC | $309,515 | |||
| 11 | $224,902 | ||||
| 12 | $156,789 | ||||
| 13 | 31 minutos | $286,427 | |||
| 14 | $220,985 | ||||
| 15 | $121,552 | ||||
| 16 | $106,283 | ||||
| 17 | $72,801 | ||||
| 18 | Iron Man | $527,314 | |||
| 19 | $185,4051 | ||||
| 20 | $539,888 | ||||
| 21 | Indiana Jones and the Kingdom of the Crystal Skull | $483,914 | |||
| 22 | $296,499 | ||||
| 23 | The Chronicles of Narnia: Prince Caspian | $209,544 | |||
| 24 | The Happening | $223,054 | |||
| 25 | Get Smart | $192,453 | |||
| 26 | Wall-E | $545,035 | |||
| 27 | $435,033 | ||||
| 28 | Kung Fu Panda | $508,559 | |||
| 29 | The Dark Knight | $805,318 | |||
| 30 | $604,025 | ||||
| 31 | $443,260 | ||||
| 32 | Journey to the Center of the Earth | $319,620 | |||
| 33 | $305,775 | ||||
| 34 | $151,955 | ||||
| 35 | $149,051 | ||||
| 36 | $114,406 | ||||
| 37 | You Don't Mess with the Zohan | $114,298 | |||
| 38 | Journey to the Center of the Earth | $89,661 | |||
| 39 | $81,495 | ||||
| 40 | Mirrors | $83,802 | |||
| 41 | $64,361 | ||||
| 42 | Mamma Mia! | $92,675 | |||
| 43 | $47,239 | ||||
| 44 | $63,630 | ||||
| 45 | Quantum of Solace | $259,998 | |||
| 46 | $154,842 | ||||
| 47 | $226,153 | High School Musical 3: Senior Year is the highest weekend opening for a musical film. | |||
| 48 | $115,978 | ||||
| 49 | $402,766 | ||||
| 50 | The Day the Earth Stood Still | $243,095 | |||
| 51 | Madagascar: Escape 2 Africa | $178,780 | |||
| 52 | Bolt | $269,313 |