| Week ending | Film | Box office | Openings |
|---|
| 1 | | Happy Feet | $10,757,456 | |
| 2 | | $6,670,578 | Blood Diamond (#5), Flicka (#12) |
| 3 | | The Pursuit of Happyness | $5,124,284 | Apocalypto (#7), Arthur and the Invisibles (#11), Guru (#19) |
| 4 | | Déjà Vu | $3,593,058 | Dreamgirls (#5), Pan's Labyrinth (#15) |
| 5 | | Epic Movie | $3,854,240 | Miss Potter (#4), Breaking and Entering (#17), (#19), The Fountain (#20) |
| 6 | | Miss Potter | $1,510,366 | Stranger Than Fiction (#5), The Last King of Scotland (#13), Perfume: The Story of a Murderer (#15) |
| 7 | | $1,140,201 | Hannibal Rising (#2), Smokin' Aces (#5), Music and Lyrics (#6), Employee of the Month (#13), Little Children (#17), Tenacious D in The Pick of Destiny (#20) |
| 8 | | Ghost Rider | $3,115,443 | Notes on a Scandal (#3), The Good Shepherd (#4) |
| 9 | | Rocky Balboa | $2,724,994 | Norbit (#2), Letters from Iwo Jima (#12) |
| 10 | | Music and Lyrics | $1,461,791 | The Illusionist (#6), Man of the Year (#7) |
| 11 | | Wild Hogs | $4,500,865 | Bobby (#8), The Hitcher (#10), The Good German (#15) |
| 12 | | $3,404,028 | Hot Fuzz (#2), Bra Boys (#4), (#5), Scoop (#6) |
| 13 | | $2,863,477 | Freedom Writers (#3), TMNT (#4), Reign Over Me (#7), Namastey London (#20) |
| 14 | | Mr. Bean's Holiday | $5,334,859 | Meet the Robinsons (#3), Becoming Jane (#5), The Lives of Others (#9), Happily N'Ever After (#14), Running with Scissors (#18) |
| 15 | | 300 | $7,638,215 | Are We Done Yet? (#6), The Namesake (#13), The Singer (#17) |
| 16 | | Mr. Bean's Holiday | $3,443,843 | Disturbia (#4), Stomp the Yard (#6), Sunshine (#8) |
| 17 | | Shooter | $2,306,217 | Perfect Stranger (#4), The Reaping (#9), Paris, je t'aime (#15), Copying Beethoven (#19) |
| 18 | | $1,311,570 | The Number 23 (#4), Curse of the Golden Flower (#8), Half Nelson (#18), Ta Ra Rum Pum (#19) |
| 19 | | Spider-Man 3 | $11,982,672 | Because I Said So (#2), The History Boys (#6), Noise (#17), The Science of Sleep (#20) |
| 20 | | $5,118,668 | 28 Weeks Later (#2), Georgia Rule (#4), Lucky You (#5) |
| 21 | | $3,235,832 | Zodiac (#2), Breach (#6), (#8) |
| 22 | | | $14,855,985 | My Best Friend (#9), Shootout at Lokhandwala (#18) |
| 23 | | $7,835,837 | Romulus, My Father (#4), The Messengers (#20) |
| 24 | | Shrek the Third | $14,698,677 | (#5), Driving Lessons (#11), (#15) |
| 25 | | $6,286,026 | Ocean's Thirteen (#2), Bridge to Terabithia (#4), Jhoom Barabar Jhoom (#10) |
| 26 | | $4,053,164 | (#2), Blades of Glory (#4), I Do (#8), Nancy Drew (#9), The Dead Girl (#13) |
| 27 | | Transformers | $11,466,168 | Clubland (#9), Apne (#18), Four Minutes (#19) |
| 28 | | $7,085,042 | Knocked Up (#2), Harry Potter and the Order of the Phoenix opening day (#3), Black Book (#14) |
| 29 | | Harry Potter and the Order of the Phoenix | $16,326,508 | La Vie en rose (#8) |
| 30 | | $6,444,039 | Premonition (#4), Evening (#5), Lucky Miles (#13), Partner (#18), Gone (#20) |
| 31 | | The Simpsons Movie | $15,816,056 | Amazing Grace (#5), In the Land of Women (#9) |
| 32 | | $7,274,035 | Licence to Wed (#3), Fracture (#4), Mr. Brooks (#8), Black Snake Moan (#12), Snow Cake (#13) |
| 33 | | Die Hard 4.0 | $5,040,919 | Sicko (#9), Chak De! India (#12) |
| 34 | | I Now Pronounce You Chuck and Larry | $3,076,680 | Black Sheep (#11), This Is England (#13), After the Wedding (#19) |
| 35 | | No Reservations | $2,195,386 | Next (#6), Heyy Babyy (#13), The Home Song Stories (#16), Boynton Beach Club (#20) |
| 36 | | The Bourne Ultimatum | $8,196,081 | Once (#9) |
| 37 | | $5,015,313 | Ratatouille (#2), The Final Winter (#10), Lady Chatterley (#16), The White Planet (#18) |
| 38 | | Hairspray | $4,532,318 | Surf's Up (#4), Forbidden Lie$ (#12) |
| 39 | | $3,218,845 | Superbad (#2), Evan Almighty (#3), Stardust (#6), Underdog (#8), (#9), December Boys (#10), (#18) |
| 40 | | Rush Hour 3 | $4,733,698 | (#13), The War on Democracy (#16) |
| 41 | | $2,589,645 | The Kingdom (#4), The Nanny Diaries (#9), The Seeker: The Dark Is Rising (#12), Away from Her (#15) |
| 42 | | Death at a Funeral | $1,720,034 | (#2), The Brave One (#5), Bhool Bhulaiyaa (#18), Laaga Chunari Mein Daag (#19) |
| 43 | | $1,684,905 | Michael Clayton (#2), Rogue Assassin (#4), A Mighty Heart (#9) |
| 44 | | Saw IV | $2,375,346 | Good Luck Chuck (#3), Eastern Promises (#7), Waitress (#13), Control (#17) |
| 45 | | Death at a Funeral | $1,782,855 | The Game Plan (#2), Death Proof (#6), The Assassination of Jesse James by the Coward Robert Ford (#10), Across the Universe (#11) |
| 46 | | $1,376,440 | Lions for Lambs (#2), 30 Days of Night (#4), Rogue (#5), Om Shanti Om (#9), Saawariya (#16), Conversations with My Gardener (#19) |
| 47 | | | $1,908,178 | Fred Claus (#2), Gabriel (#5) |
| 48 | | The Heartbreak Kid | $2,704,969 | Halloween (#6), Rescue Dawn (#11), Balls of Fury (#19), Dhan Dhana Dhan Goal (#20) |
| 49 | | Beowulf | $3,063,544 | Daddy Day Camp (#7), Into the Wild (#8), Aaja Nachle (#16) |
| 50 | | Bee Movie | $3,723,251 | Hitman (#2), 1408 (#4), Twice Upon a Time (#19) |
| 51 | | $3,352,688 | Mr. Magorium's Wonder Emporium (#2), Hunting and Gathering (#12) |
| 52 | | | $4,488,750 | Boxing Day openings: The Golden Compass (#4), (#5), Atonement (#6), Enchanted (#7), No Country for Old Men (#12), P.S. I Love You (#13), The Darjeeling Limited (#18) |
|
