Limestone Canyon virus explained

Limestone Canyon virus (LSC) is a single-stranded, negative-sense RNA zoonotic Orthohantavirus that is genetically similar to Sin Nombre orthohantavirus which causes Hantavirus pulmonary syndrome (HPS) in humans. HPS causing hantaviruses are found only in the United States and South America.^[1]

LSC has not been shown to cause HPS in humans.^[2]

Reservoir

The virus was isolated from the brush mouse (Peromyscus boylii).^[3] Phylogenetic analysis of M genome segment showed LSC to be very distinct from other Peromyscus-borne viruses. Other Peromyscus-associated hantaviruses include Sin Nombre orthohantavirus (SNV), New York orthohantavirus (NYV), and Monongahela virus (MGLV).^[1]

See also

• 1993 Four Corners hantavirus outbreak

External links

• Sloan Science and Film / Short Films / Muerto Canyon by Jen Peel 29 minutes
• "Hantaviruses, with emphasis on Four Corners Hantavirus" by Brian Hjelle, M.D., Department of Pathology, School of Medicine, University of New Mexico
• CDC's Hantavirus Technical Information Index page
• Viralzone: Hantavirus
• Virus Pathogen Database and Analysis Resource (ViPR): Bunyaviridae
• Occurrences and deaths in North and South America

Notes and References

1. Sanchez AJ, Abbott KD, Nichol ST. Genetic identification and characterization of limestone canyon virus, a unique Peromyscus-borne hantavirus. Virology. 2001 Aug 1;286(2):345–53.
2. Web site: DHS Guidelines for rodent hantavirus surveillance . 2013-07-11 . dead . https://web.archive.org/web/20121113130839/http://www.cdph.ca.gov/HealthInfo/discond/Documents/CDHSGuidelinesforrodenthantavirussurveillance.pdf . 2012-11-13 .
3. Web site: ICTV 9th Report (2011) Bunyaviridae . International Committee on Taxonomy of Viruses (ICTV) . 7 March 2019 . en .