| Competition: | Liga Nacional |
| Season: | 1980–81 |
| Winners: | Real España (4th) |
| Relegated: | None |
| Continentalcup1: | CONCACAF Champions' Cup |
| Continentalcup1 Qualifiers: | Real España Marathón |
| Continentalcup2: | Copa Fraternidad |
| Continentalcup2 Qualifiers: | Real España Marathón Olimpia Vida |
| League Topscorer: | Altamirano (13) |
| Total Goals: | 358 |
| Matches: | 158 |
| Prevseason: | 1979–80 |
| Nextseason: | 1981–82 |
| Updated: | 17 December 1980 |
The 1980–81 Honduran Liga Nacional season was the 15th edition of the Honduran Liga Nacional. The format of the tournament remained the same as the previous season. Real C.D. España won the title after defeating C.D. Marathón in a 3-series final.[1] Both teams qualified to the 1981 CONCACAF Champions' Cup. Additionally, Real España, Marathón, Club Deportivo Olimpia and C.D.S. Vida obtained berths to the 1981 Copa Fraternidad. Due to the national team's participation at the 1982 FIFA World Cup qualifiers, the league defined that no relegation was to take place this season. C.D. Platense which finished last, was financially penalized though.[2]
Luis O. Altamirano (Broncos) with 13 goals| Atlético Morazán | |||
|---|---|---|---|
| José Luis Cruz Figueroa | José Estanislao "Tanayo" Ortega | Noel Omar Renderos | |
| Héctor "Lin" Zelaya | |||
| Broncos | |||
| Luis Oswaldo "Che" Altamirano | Iván Ramos | Dennis Williams | |
| Iván Guerra | César Humberto Carranza | Luis Rosales Brand | |
| German "Loco" Guzmán | Carlos Mondragón | Orlando Flores | |
| Cruz Ramón Serrano "Guaya" Cruz |  Pedro Pinheiro | Rubén Guardado | |
| Marcial Bonilla | Orlando Rodríguez | Luis Alberto Escaurizza | |
| José Marcial "Canelo" Murillo | "Yuyuguita" Flores | Marco Tulio Cacho | |
| Samuel "Chucho" Armijo | Marco Tulio Cárcamo | Isidro Arriola | |
| Enrique "Pilo" Soriano | José Ramón Hinds | Antonio Almendárez | |
| Jairo Lezama | Rigoberto "Chombo" Aguilar | Mario López | |
| Oscar "Zorro" Lezama | |||
| Marathón | |||
| Jorge Phoyoú | Wilfredo Brown | Jorge Alberto "Cuca" Bueso Iglesias | |
| Roberto Reynaldo "Robot" Bailey Sargent | Jorge Martínez | Alberto Merelles | |
| Francisco Javier Toledo | Ramón "Albañil" Osorio | Arturo Torres "Pacharaca" Bonilla | |
| Carlos Mejía | José Ángel Peña | Oswaldo Zaldívar | |
| Alfredo Dimaio | Antonio "Gato" Pavón Molina | Hernán Santiago "Cortés" García Martínez | |
| René "Maravilla" Suazo | José Martínez | Juan Carlos Weber | |
| Francisco Zelaya Pastrana | Arturo Payne | Richard Kenneth Payne | |
| Félix Concepción Carranza | Gilberto Leonel Machado García | Celso Fredy Güity | |
| Rigoberto Castro | Rolando Padilla "Moro" Bardales | Margarito Castillo | |
| Fernando Figueroa | Carlos Guevara | Luis Alonso Guzmán Velásquez | |
| Juan Contreras | Óscar Romero | ||
| Motagua | |||
| German "Loco" Guzmán | Mario Hernán Juviny Carreño | Luis Alberto "Chito" Reyes | |
| Rigoberto Sosa | Víctor Manuel Chávez | José Salomón "Turco" Nazzar | |
| Olimpia | |||
| Óscar Banegas | Darío Cribas | Roberto Valentín "Pirata" Fernández | |
| Alejandro "Indio" Ruiz | José Batiz | Víctor Calero Lozano | |
| Rigoberto Ruiz | Emilio Martínez | Fredy Ríos | |
| Basilio Avila | Ramón Antonio "Pilín" Brand | Rigoberto "Shula" Gómez | |
| Raúl Cocherari | José Luis Januario | Jorge Alberto "Perro" González | |
| Carlos Solís | Óscar García | Víctor Romero | |
| Daniel Zapata | Antonio Alemán | Héctor Uclés | |
| Nelson de Moraes | Alcides Carota | Arturo Cáceres | |
| Horacio Parham Castro | |||
| Platense | |||
| Juan Jerezano | Jorge Luis Mancía | Tomás Cedricks Ewens "Quito" Wagner | |
| Alex Rodríguez | Carlos Cruz Colindres | Antonio Laing | |
| Modesto Ayestas | |||
| Real España | |||
| Julio César "El Tile" Arzú | Jimmy Steward | Clinton Campbell | |
| Didier Gutiérrez | Carlos Orlando Caballero | Jorge Alberto Centurión | |
| Walter Jimminson | Allan Costly | Víctor Hugo Salgado | |
| Julio Roberto "Chino" Ortiz | Francisco García | Marcos Campbell | |
| German "Cacique" Castro | Javier Latreza | Miguel Antonio "Hino" Mathews | |
| Edith Hernando Contreras | Enrique "Fantasma" Mendoza | Jimmy James Bailey | |
| Javier Chavarría | Julio del Carmen Tapia Callao | Jaime Villegas | |
| Junior Rashford Costly | Roberto "Sargento" Barahona | Juan Carlos Espinoza | |
| Carlos Solano | Marcos Lacayo | José Antonio "Gin" García | |
| Oscar Velásquez | Roscoe Charles | Carlos Rivera | |
| Edelmín "Pando" Castro | Alberto Chedrany | ||
| Universidad | |||
| Raúl David Fúnez | Olvin Elvir | Walter "Estupiñán" Amador | |
| Daniel "Diablo" Sambulá | Edimar Luiz Marques | ||
| Victoria | |||
| Jorge Alberto "Camioncito" Duarte | Luis Alonso "Chorompo" Zúniga | Francisco Jiménez | |
| Efraín Martínez "Diablillo" Amaya | José Reynaldo Villagra | Fausto Humberto "Chiva" Ruiz | |
| Benedicto Ordóñez | Ramón "Liebre" Guardado | Miguel Angel "Primitivo" Ortiz | |
| David Goff | |||
| Vida | |||
| Matilde Selím Lacayo | Roberto "Macho" Figueroa | Junior Mejía | |