| Lezica–Melilla | |
| Settlement Type: | Barrio |
| Image Map1: | Montevideo Lezica-Melilla.png |
| Map Caption1: | Location of Lezica–Melilla in Montevideo |
| Subdivision Type: | Country |
| Subdivision Name: |  Uruguay |
| Subdivision Type1: | Department |
| Subdivision Name1: | Montevideo Department |
| Subdivision Type2: | City |
| Coordinates: | -34.7783°N -56.2767°W |
Lezica–Melilla is a barrio (neighbourhood or district) of Montevideo, Uruguay.
This barrio borders Paso de la Arena–Los Bulevares and Conciliación to the south, San José Department to the west with Santa Lucía River forming the natural border between them, Canelones Department to the north, Colón Sudeste–Abayubá and Colón Centro y Noroeste to the east.
Lezica is the west part of Villa Colón and its main avenue is Avenida Lezica, ending at the Ángel S. Adami Airport.