Alexander Cools Explained

Alexander Cools
Birth Date:1941
Birth Place:The Hague, Netherlands
Death Place:Nijmegen, The Netherlands
Nationality:Dutch
Fields:Psychoneuropharmacology
Workplaces:Radboud University Nijmegen
Alma Mater:Radboud University Nijmegen
Thesis Title:The Caudate Nucleus and Neurochemical Control of Behaviour: The Function of Dopamine and Serotonin in the Caput Nuclei Caudati of Cats
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Thesis Year:1973
Doctoral Advisor:Jacques van Rossum, Jo Vossen
Known For:Research on dopamine and the basal ganglia
Awards:Distinguished Achievement Award (EBPS)
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Signature:Signature Cools.jpg

Alexander ("Lex") Rudolf Cools (1941 in The Hague – 7 September 2013 in Nijmegen) was a Dutch behavioral pharmacologist.

He obtained his Ph.D. under the supervision of Jacques van Rossum and Jo Vossen in 1973 at the Radboud University Nijmegen,[1] where he was a professor from 1985 until his retirement in 2006.[2] [3] In 2014, a special issue of the scientific journal Behavioural Pharmacology was dedicated to his memory.[4] Cools was one of the founders of the European Behavioural Pharmacology Society and its second president. In 2003 he received that society's Distinguished Achievement Award.

In 1976, Cools was the first to propose the existence of different types of dopamine receptors,[5] an essentially correct claim that initially was generally dismissed.

Besides his work on dopamine, Cools is mostly known for his work on the basal ganglia and the dorsal and ventral striatum.[6]

Notes and References

  1. Cools . A.R. . The Caudate Nucleus and Neurochemical Control of Behaviour: The Function of Dopamine and Serotonin in the Caput Nuclei Caudati of Cats . Ph.D. . 1973 . Drukkerij Brakkenstein . 001179054 . 76379116.
  2. 10.1007/s00213-014-3583-5 . 24770629 . Alexander Rudolf Cools (1942–2013) . . 231 . 11 . 2219–2222 . 2014 . Ellenbroek . Bart A. . Homberg . Judith . Verheij . Miche l. Spooren . Will . Van Den Bos . Ruud . Martens . Gerard. free .
  3. 10.1097/FBP.0000000000000101 . 25692200 . Alexander R. Cools (1941–2013) . Behavioural Pharmacology . 26 . 1–2 . 4–5 . 2015 . Robbins . Trevor . 10471063 . Trevor Robbins.
  4. 10.1097/FBP.0000000000000125 . 25539481 . The behavioural pharmacology of the basal ganglia . Behavioural Pharmacology . 26 . 1–2 . 1–2 . 2015 . Willner . Paul . Bergman . Jack . Vanderschuren . Louk . Ellenbroek . Bart. 1874/314557 . 5455276 . free .
  5. Cools . AR . van Rossum . JM . Excitation-mediating and inhibition-mediating dopamine-receptors: a new concept towards a better understanding of electrophysiological, biochemical, pharmacological, functional and clinical data . . 45 . 3 . 243–254 . 1976 . 175391 . 10.1007/bf00421135. 40366909 .
  6. van den Bos . Ruud . The dorsal striatum and ventral striatum play different roles in the programming of social behaviour: a tribute to Lex Cools . Behavioural Pharmacology . February 2015 . 26 . 6–17 . 10.1097/FBP.0000000000000110. 25545961 .