Corbadrine Explained

Corbadrine (INN; marketed as Neo-Cobefrine), also known as levonordefrin (USAN) and α-methylnorepinephrine, is a catecholamine sympathomimetic used as a topical nasal decongestant and vasoconstrictor in dentistry in the United States,[1] [2] (usually in a pre-mixed solution with local anesthetics, such as mepivacaine).[3]

Corbadrine is also a metabolite of the antihypertensive drug methyldopa,[4] and plays a role in its pharmacology and effects.

See also

Notes and References

  1. Book: Morton I, Morton IK, Hall JM . Concise Dictionary of Pharmacological Agents: Properties and Synonyms. 31 October 1999. Springer Science & Business Media. 978-0-7514-0499-9. 164–.
  2. Book: Index Nominum 2000: International Drug Directory. January 2000. Taylor & Francis. 978-3-88763-075-1. 275–.
  3. Web site: DailyMed — Search results for levonordefrin. DailyMed. 20 February 2016.
  4. Sjoerdsma A, Vendsalu A, Engelman K . Studies on the Metabolism and Mechanism of Action of Methyldopa . Circulation . 28 . 4 . 492–502 . October 1963 . 14068757 . 10.1161/01.CIR.28.4.492 . free .

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