Levodropropizine Explained

Levodropropizine is a cough suppressant. It is the levo isomer of dropropizine. It acts as a peripheral antitussive, with no action in the central nervous system.[1] It does not cause side effects such as constipation or respiratory depression which can be produced by opioid antitussives such as codeine and its derivatives.In September 2021, Korea United Pharm file lawsuits against 15 drug manufacturers as patent infringement protection for its 2017 registered antitussive drug Levotics CR Tab. (levodropropizine). The cases are anchored on violation of its patent for "Method for Preparing Sustained-Release Tablets Containing Levodropropizine."[2] In September 2023, KUP signed a five-year $52.1 million contract with MCQ, a Thai-based pharmaceutical company, for supply of its mucoactive drug, Levotics CR Tab (levodropropizine).[3]

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Notes and References

  1. De Blasio F, Dicpinigaitis PV, Rubin BK, De Danieli G, Lanata L, Zanasi A . An observational study on cough in children: epidemiology, impact on quality of sleep and treatment outcome . Cough . 8 . 1 . 1 . January 2012 . 22269875 . 3274450 . 10.1186/1745-9974-8-1 . free .
  2. News: Chan-hyuk . Kim . Korea United Pharm sues 15 drugmakers to protect cough suppressant's patent. July 29, 2024 . . September 9, 2021.
  3. News: Korea United Pharm to supply mucoactive drugs worth $52 million to Thailand. July 29, 2024 . Korea Biomedical Review. September 9, 2023.