Levi Garraway Explained

Levi Garraway
Birth Place:Oakland, California, US
Education:AB, biochemical sciences, Harvard College
MD, PhD, Harvard Medical School
Parents:Annie Marie Watkins Garraway
Michael Garraway (died 1999)
Relatives:Levi Watkins (uncle)
Spouse:Gisele
Workplaces:Harvard University
Roche Holding AG
Eli Lilly and Company
Foundation Medicine
Dana–Farber Cancer Institute
Broad Institute
Titles:Chief Medical Officer at Roche Holding AG
Occupation:Oncologist

Levi A. Garraway (born in 1968)[1] is an American oncologist. His research team was among the first to adapt genomics technologies to enable scalable, high-throughput clinical approaches to cancer gene mutation profiling. As a result, he was inducted into the American Society for Clinical Investigation, American Association for Cancer Research, and National Academy of Medicine.

Early life and education

Garraway was born to parents Annie Marie Watkins Garraway and Michael Garraway[2] in Oakland, California.[3] His mother earned a Ph.D. in mathematics and became a department chair at AT&T Bell Labs. As well, his uncle Levi Watkins was the first African-American student admitted to and graduate from Vanderbilt University School of Medicine.[2] His father, an émigré from the Caribbean, was also a professor of plant biology at Ohio State University.[2] [4] While Garraway was in high school, he hung around the university lab and helped his father with experiments.[5]

Garraway received his A.B. in biochemical sciences from Harvard College and his medical degree and Ph.D. from Harvard Medical School. He then completed his internship and residency in internal medicine at the Massachusetts General Hospital and his fellowship training in medical oncology at the Dana–Farber Cancer Institute.[6] His choice to pursue a medical degree on top of his PhD was the result of his academic family, specifically his uncle.[7]

Career

Upon completing his fellowship, Garraway became an associate member of the Broad Institute and an assistant professor in the Department of Medical Oncology at the Dana–Farber Cancer Institute.[5] At Broad Institute, Garraway's research involved the systematic characterization of critical and targetable mechanisms enacted by common genomic alterations in human tumors. His research team was among the first to adapt genomics technologies to enable scalable, high-throughput clinical approaches to cancer gene mutation profiling.[8] In 2007, Garraway and Matthew Meyerson published a paper detailing a method for large-panel testing of 238 DNA mutations. This led to the establishment of Foundation Medicine.[9] As a result of his discovery, Garraway was eleceted a member of the American Society for Clinical Investigation in 2009.[8]

During his tenure at the Broad Institute, Garraway also became the co-leader of the Cancer Genetics Program at Dana-Farber/Harvard Cancer Center and an associate professor at Dana–Farber Cancer Institute and Harvard Medical School. In 2012, Garraway was a recipient of the Paul Marks Prize for Cancer Research from the Memorial Sloan-Kettering Cancer Center as a "promising scientist under the age of 45 in recognition of his contributions to cancer research."[10] He also earned the 19th annual Herbert and Maxine Block Memorial Lectureship Award for Achievement in Cancer.[11]

On September 14, 2016, Garraway was appointed the Senior Vice President of Global Oncology at Eli Lilly and Company, succeeding Richard Gaynor.[12] In October 2019, Garraway started his new leadership role as Roche Holding AG's Chief Medical Officer.[7] He was also elected to the American Association for Cancer Research for "visionary contributions to the establishment of genomics-driven precision cancer medicine by pioneering high-throughput adaptation of genomic technologies to profile human tumors to identify actionable cancer gene mutations, allowing for precise patient population stratification."[13]

During the COVID-19 pandemic, Garraway was elected a member of the National Academy of Medicine "for the discovery of genetic drivers of melanoma, prostate cancer, and other malignancies, the discovery of mechanisms of response and resistance to anticancer therapies in melanoma and other cancer types, pioneering platforms and approaches to cancer precision medicine, and incorporating precision medicine principles in therapeutic development."[14]

Personal life

Garraway and his wife Gisele have two children together; a son and a daughter.[5], his younger sister Isla is a urologist and surgeon at University of California, Los Angeles's Jonsson Comprehensive Cancer Center.[15]

Notes and References

  1. Web site: Dr. Levi Garraway CV . roche.com . May 28, 2023.
  2. Garraway . Levi A. . Believe the miracles: of biomedical science and human suffering . . December 1, 2016 . 126 . 12 . 4716–4722 . 10.1172/JCI90893 . 27906693 . 5127662 .
  3. Web site: Special Spotlight: Levi A. Garraway, M.D., Ph.D., Receives Prestigious Jane Cooke Wright Award from American Association for Cancer Research . cancer.gov . May 28, 2021 . April 17, 2014.
  4. Web site: Garraway details family's key role in shaping career path . news.vumc.org . May 28, 2021 . October 12, 2017.
  5. News: Rimas . Andrew . He trolls genome for cancer clues . May 28, 2021 . The Boston Globe . September 24, 2007. newspapers.com.
  6. Web site: LEVI GARRAWAY . broadinstitute.org . . May 28, 2021.
  7. Web site: Levi Garraway: A passion for purpose . roche.com . . May 28, 2021 . October 8, 2019.
  8. Web site: Levi Garraway, MD, PhD . the-asci.org . . May 28, 2021.
  9. News: Burke. Afrienne. Foundation Medicine: Personalizing Cancer Drugs . MIT Technology Review . February 21, 2012 . May 28, 2021 .
  10. Web site: Meade-Kelly . Veronice . Levi Garraway awarded Paul Marks Prize for Cancer Research . broadinstitute.org . May 28, 2021 . September 26, 2013.
  11. Web site: Researcher receives achievement award . healio.com . May 28, 2021 . December 1, 2012.
  12. Web site: Levi Garraway, M.D., Ph.D., to become Senior Vice President of Global Oncology at Lilly, Succeeding Richard Gaynor, M.D., Who is Retiring after a Distinguished Career . investor.lilly.com . May 28, 2021 . September 14, 2016.
  13. Web site: LEVI A. GARRAWAY, MD, PHD . aacr.org . May 28, 2021.
  14. Web site: National Academy of Medicine elects 100 new members . eurekalert.org . Eurekalert . May 28, 2021 . October 19, 2020.
  15. Web site: Curlee . Elizabeth . A Deeper Reason For Cancer Research . cbsnews.com . CBS News . May 28, 2021 . June 14, 2007.