Leucine N-acetyltransferase explained

leucine N-acetyltransferase
Ec Number:	2.3.1.66
Cas Number:	75496-56-9
Go Code:	0050050

In enzymology, a leucine N-acetyltransferase is an enzyme that catalyzes the chemical reaction

acetyl-CoA + L-leucine

\rightleftharpoons CoA + N-acetyl-L-leucine

Thus, the two substrates of this enzyme are acetyl-CoA and L-leucine, whereas its two products are CoA and N-acetyl-L-leucine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:L-leucine N-acetyltransferase. This enzyme is also called leucine acetyltransferase.

References

• Suzukake S, Hayashi H, Hori M, Umezawa H . 1982 . Biosnthesis of leupeptin III. Isolation and properties of an enzyme synthesizing acetyl-L-leucine . J. Antibiot. . 33 . 857 - 862 . 7429989 . 8 . 10.7164/antibiotics.33.857 . free .