| Lettopalena | |
| Official Name: | Comune di Lettopalena |
| Coordinates: | 42°N 24°W |
| Province: | (CH) |
| Mayor: | Carolina De Vitis |
| Area Total Km2: | 20 |
| Population Footnotes: | [1] |
| Population Total: | 349 |
| Population As Of: | 31 March 2017 |
| Population Demonym: | Lettopalenesi or Lettesi |
| Elevation M: | 680 |
| Saint: | St. Vincent Ferrer |
| Day: | 5 April |
| Postal Code: | 66010 |
| Area Code: | 0872 |
Lettopalena (Abruzzese: Neapolitan: Lètte) is a comune and town in the province of Chieti in the Abruzzo region of south-eastern Italy.