| Letaba River | |
| Name Etymology: | Meaning "sandy river" in Northern Sotho language |
| Pushpin Map: | South Africa |
| Pushpin Map Caption: | Location of the Letaba River's mouth |
| Subdivision Type1: | Country |
| Subdivision Name1: | South Africa |
| Subdivision Type3: | Region |
| Subdivision Name3: | Limpopo Province |
| Source1 Location: | Gauteng Province |
| Source2 Location: | Soutpansberg |
| Mouth: | Olifants River |
| Mouth Location: | Limpopo Province |
| Mouth Coordinates: | -23.9894°N 31.8267°W |
| Basin Size: | 67000km2 |
| Tributaries Left: | Nharhweni River, Ngwenyeni River, Klein Letaba River, Molototsi River, Nsama River |
| Tributaries Right: | Groot Letaba River, Nwanedzi River, Makhadzi River |
The Letaba River (Afrikaans: Letabarivier), also known as Leţaba, Lehlaba or Ritavi, is a river located in eastern Limpopo Province, South Africa. It is one of the most important tributaries of the Olifants River.
It starts at the confluence of the Groot Letaba River and Klein Letaba River, whence they continue their journey eastwards through the Lowveld as the Letaba River. It joins the Olifants River in the foothills of the Lebombo Mountains, near South Africa's border with Mozambique. In Mozambique, the latter river is called the Rio Elefantes.
Tributaries include the Middle Letaba River, Nharhweni River, Ngwenyeni River, Nwanedzi River, Molototsi River, Nsama River, and Makhadzi River.
thumb|none|450px|Game animals along its banks, near Letaba camp, central Kruger Park