| Lesme | |
| Commune Status: | Commune |
| Insee: | 71255 |
| Postal Code: | 71140 |
| Arrondissement: | Charolles |
| Canton: | Digoin |
| Mayor: | Thierry Bernardin[1] |
| Term: | 2020 - 2026 |
| Coordinates: | 46.65°N 3.7167°W |
| Elevation M: | 236 |
| Elevation Min M: | 202 |
| Elevation Max M: | 260 |
| Area Km2: | 5.08 |
Lesme (in French pronounced as /lɛm/) is a commune in the Saône-et-Loire department in the region of Bourgogne-Franche-Comté in eastern France.