| Leslie River | |
| Pushpin Map: | New Zealand#New Zealand South Island |
| Pushpin Map Size: | 270px |
| Pushpin Map Caption: | Mouth of the Leslie River |
| Source1: | Wharepapa / Arthur Range |
| Source1 Coordinates: | -41.2046°N 172.6829°W |
| Mouth Location: | Karamea River |
| Mouth Coordinates: | -41.2329°N 172.5081°W |
| Subdivision Type1: | Country |
| Subdivision Name1: | New Zealand |
| Length: | 12km (07miles) |
| Progression: | Leslie River → Karamea River → Ōtūmahana Estuary → Karamea Bight → Tasman Sea |
| Tributaries Left: | Twins Creek, Arthur Creek, Meyer Stream, Wilkinson Creek |
| Tributaries Right: | Peel Stream, Hodges Stream |
The Leslie River is a river of the northwest of New Zealand's South Island located in the Buller District. A tributary of the Karamea River, the Leslie flows west from the Wharepapa / Arthur Range, meeting the Karamea east of the town of Karamea. The river's entire length is within Kahurangi National Park.