| Party: | African National Congress |
| Office1: | Member of the National Assembly |
| Termstart1: | June 1999 |
| Termend1: | April 2004 |
| Citizenship: | South Africa |
| Birth Date: | 11 September 1962 |
| Constituency1: | North West |
Lesiba Moses Kgwele (born 11 September 1962) is a South African politician and communications strategist. He represented the African National Congress (ANC) in the National Assembly for a single term from 1999 to 2004, serving the North West constituency.[1] He left Parliament after the 2014 general election.
He later served as spokesman and head of communications for the Premier of the North West during the tenure of Premier Thandi Modise.[2] [3] Shortly after Modise left the office, in July 2014, Kgwele was sacked for misconduct. The government said that the disciplinary hearing had been initiated in March 2013 and had found Kgwele guilty of gross insubordination.[4] Kgwele said that the misconduct charges were "part of a much bigger orchestrated plot to purge and ultimately destroy me" based on "a personal grudge".[5]