| Les MacPherson | |
| Fullname: | Leslie Mitchell MacPherson |
| Birth Date: | 17 May 1880 |
| Birth Place: | Balranald, New South Wales |
| Death Place: | Melbourne |
| Originalteam: | Cumloden College |
| Height: | 175 cm |
| Weight: | 67 kg |
| Statsend: | 1899 |
| Years1: | 1898–99 |
| Games Goals1: | 5 (1) |
Leslie Mitchell MacPherson (17 May 1880 – 14 June 1941) was an Australian rules footballer who played with Melbourne in the Victorian Football League (VFL).[1]